STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dfer_5264Hypothetical protein; KEGG: ENSAPMG00000010754; K10421 CAP-Gly domain- containing linker protein 1. (870 aa)    
Predicted Functional Partners:
Dfer_5265
Hypothetical protein.
       0.773
Dfer_5263
Hypothetical protein.
       0.675
Dfer_5266
Hypothetical protein.
       0.601
Dfer_0819
KEGG: ppf:Pput_2839 phosphatidylinositol-specific phospholipase C, X region.
    
 
 0.451
Dfer_2768
PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; KEGG: chu:CHU_1614 DNA topoisomerase IV subunit B.
   
 
 0.428
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.428
Dfer_3086
PFAM: glycoside hydrolase family 18; SMART: chitinase II; KEGG: sru:SRU_2812 chitinase A1 precursor; Belongs to the glycosyl hydrolase 18 family.
    
 
 0.415
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.404
Your Current Organism:
Dyadobacter fermentans
NCBI taxonomy Id: 471854
Other names: D. fermentans DSM 18053, Dyadobacter fermentans DSM 18053, Dyadobacter fermentans str. DSM 18053, Dyadobacter fermentans strain DSM 18053
Server load: low (26%) [HD]