STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV23617.1Methyltransferase, MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. (341 aa)    
Predicted Functional Partners:
ACV23619.1
Hypothetical protein; Belongs to the uroporphyrinogen decarboxylase family.
 
  
 
0.979
ACV22969.1
Predicted cobalamin binding protein; PFAM: B12 binding domain; B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family; methylmalonyl-CoA mutase C-terminal domain.
 
 0.976
ACV23590.1
Predicted cobalamin binding protein; PFAM: B12 binding domain; B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family.
 
 0.976
ACV23620.1
Uncharacterized metal-binding protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain.
 
    0.938
ACV23618.1
Hypothetical protein.
 
     0.837
ACV21758.1
Protoporphyrinogen oxidase; PFAM: FAD dependent oxidoreductase.
  
  
 0.554
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
  
 0.549
ACV23621.1
Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.
 
    0.540
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 
 0.508
ACV23622.1
Predicted GTPase, G3E family; PFAM: CobW/HypB/UreG, nucleotide-binding domain.
 
    0.483
Your Current Organism:
Slackia heliotrinireducens
NCBI taxonomy Id: 471855
Other names: S. heliotrinireducens DSM 20476, Slackia heliotrinireducens DSM 20476, Slackia heliotrinireducens str. DSM 20476, Slackia heliotrinireducens strain DSM 20476
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