STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Jden_0358PFAM: RelA/SpoT domain protein; KEGG: bha:BH1885 hypothetical protein. (249 aa)    
Predicted Functional Partners:
Jden_1363
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
  
0.928
Jden_0852
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: met:M446_0533 adenylate/guanylate cyclase.
     
  0.900
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.900
Jden_1221
KEGG: mxa:MXAN_6299 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
     
  0.900
Jden_1579
KEGG: abo:ABO_0867 hypothetical protein.
     
  0.900
Jden_1920
PFAM: Ppx/GppA phosphatase; KEGG: scl:sce1705 hypothetical protein.
     
  0.900
Jden_2207
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: mmr:Mmar10_0305 anaerobic ribonucleoside triphosphate reductase.
     
  0.900
Jden_0682
3,4-dihydroxy-2-butanone 4-phosphate synthase; KEGG: gox:GOX0980 3,4-dihydroy-2-butanone 4- phosphate synthase/GTP cyclohydrolase II; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; In the N-terminal section; belongs to the DHBP synthase family.
     
  0.800
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
     
  0.800
folE
KEGG: bcy:Bcer98_1234 GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I.
     
  0.800
Your Current Organism:
Jonesia denitrificans
NCBI taxonomy Id: 471856
Other names: J. denitrificans DSM 20603, Jonesia denitrificans DSM 20603, Jonesia denitrificans str. DSM 20603, Jonesia denitrificans strain DSM 20603
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