STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Jden_0982KEGG: ank:AnaeK_2164 UTP-GlnB uridylyltransferase, GlnD; PFAM: GlnD PII-uridylyltransferase; metal-dependent phosphohydrolase HD sub domain; DNA polymerase beta domain protein region; SMART: metal-dependent phosphohydrolase HD region. (571 aa)    
Predicted Functional Partners:
Jden_0981
PFAM: nitrogen regulatory protein P-II; KEGG: rce:RC1_1257 nitrogen regulatory protein P-II.
 
 
 0.998
Jden_0980
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: dal:Dalk_5098 ammonium transporter.
 
   
 0.939
Jden_1219
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: glo:Glov_3016 glutamate synthase (ferredoxin).
     
 0.847
Jden_1486
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
 
   
 0.812
Jden_1484
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: afw:Anae109_4400 glutamine synthetase, type I.
 
   
 0.795
Jden_1487
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sat:SYN_01628 glutamine synthetase.
     
 0.751
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.675
Jden_0984
PFAM: amidohydrolase; KEGG: ccs:CCNA_00302 parathion hydrolase.
       0.602
Jden_2201
TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta- component ferrodoxin domain protein; KEGG: rso:RSp1222 nitrite reductase NADPH large subunit.
      
 0.519
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.502
Your Current Organism:
Jonesia denitrificans
NCBI taxonomy Id: 471856
Other names: J. denitrificans DSM 20603, Jonesia denitrificans DSM 20603, Jonesia denitrificans str. DSM 20603, Jonesia denitrificans strain DSM 20603
Server load: low (12%) [HD]