node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Jden_0165 | Jden_0814 | Jden_0165 | Jden_0814 | PFAM: Rhomboid family protein; KEGG: aba:Acid345_1881 rhomboid-like protein. | KEGG: pfl:PFL_0421 sec-independent translocase. | 0.766 |
Jden_0165 | tatA | Jden_0165 | Jden_1290 | PFAM: Rhomboid family protein; KEGG: aba:Acid345_1881 rhomboid-like protein. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.730 |
Jden_0814 | Jden_0165 | Jden_0814 | Jden_0165 | KEGG: pfl:PFL_0421 sec-independent translocase. | PFAM: Rhomboid family protein; KEGG: aba:Acid345_1881 rhomboid-like protein. | 0.766 |
Jden_0814 | ftsY | Jden_0814 | Jden_0979 | KEGG: pfl:PFL_0421 sec-independent translocase. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.745 |
Jden_0814 | guaA | Jden_0814 | Jden_0650 | KEGG: pfl:PFL_0421 sec-independent translocase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.961 |
Jden_0814 | secA | Jden_0814 | Jden_1822 | KEGG: pfl:PFL_0421 sec-independent translocase. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.740 |
Jden_0814 | secD | Jden_0814 | Jden_1366 | KEGG: pfl:PFL_0421 sec-independent translocase. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.675 |
Jden_0814 | tatA | Jden_0814 | Jden_1290 | KEGG: pfl:PFL_0421 sec-independent translocase. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.790 |
Jden_0814 | tatC | Jden_0814 | Jden_1291 | KEGG: pfl:PFL_0421 sec-independent translocase. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.976 |
Jden_1292 | lnt | Jden_1292 | Jden_1294 | PFAM: DEAD/DEAH box helicase domain protein; DSH domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: RNA helicase involved in mRNA catabolism. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.604 |
Jden_1292 | tatA | Jden_1292 | Jden_1290 | PFAM: DEAD/DEAH box helicase domain protein; DSH domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: RNA helicase involved in mRNA catabolism. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.640 |
Jden_1292 | tatC | Jden_1292 | Jden_1291 | PFAM: DEAD/DEAH box helicase domain protein; DSH domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: RNA helicase involved in mRNA catabolism. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.759 |
ftsY | Jden_0814 | Jden_0979 | Jden_0814 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | KEGG: pfl:PFL_0421 sec-independent translocase. | 0.745 |
ftsY | secA | Jden_0979 | Jden_1822 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.976 |
ftsY | secD | Jden_0979 | Jden_1366 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.747 |
ftsY | secY | Jden_0979 | Jden_0607 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.993 |
ftsY | tatA | Jden_0979 | Jden_1290 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.665 |
ftsY | tatC | Jden_0979 | Jden_1291 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.735 |
guaA | Jden_0814 | Jden_0650 | Jden_0814 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | KEGG: pfl:PFL_0421 sec-independent translocase. | 0.961 |
guaA | secY | Jden_0650 | Jden_0607 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.444 |