STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Jden_1969TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: mgm:Mmc1_0714 5-formyltetrahydrofolate cyclo- ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (214 aa)    
Predicted Functional Partners:
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.931
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.923
pheT
KEGG: afw:Anae109_1884 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
 
  
 0.724
Jden_1970
TIGRFAM: regulatory protein, FmdB family; KEGG: aba:Acid345_0034 type I antifreeze protein.
       0.718
Jden_0165
PFAM: Rhomboid family protein; KEGG: aba:Acid345_1881 rhomboid-like protein.
  
    0.667
Jden_1967
PFAM: GCN5-related N-acetyltransferase; KEGG: oca:OCAR_4695 ribosomal-protein-alanine N- acetyltransferase.
  
    0.666
Jden_1240
TIGRFAM: molybdenum cofactor biosynthesis protein C; molybdenum cofactor synthesis domain protein; PFAM: molybdopterin cofactor biosynthesis MoaC region; molybdopterin binding domain; KEGG: abc:ACICU_02122 molybdenum cofactor biosynthesis protein.
  
  
 0.594
Jden_1968
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
       0.578
Jden_1966
KEGG: similar to Sp17 protein.
       0.491
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.486
Your Current Organism:
Jonesia denitrificans
NCBI taxonomy Id: 471856
Other names: J. denitrificans DSM 20603, Jonesia denitrificans DSM 20603, Jonesia denitrificans str. DSM 20603, Jonesia denitrificans strain DSM 20603
Server load: low (14%) [HD]