STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Jden_2199PFAM: Uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; KEGG: aeh:Mlg_1707 uroporphyrinogen III synthase HEM4. (372 aa)    
Predicted Functional Partners:
Jden_2200
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: yen:YE2748 putative uroporphyrin-III C- methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.989
Jden_2492
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.982
Jden_0658
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bpe:BP1055 siroheme synthase.
 
 
 0.979
Jden_2201
TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta- component ferrodoxin domain protein; KEGG: rso:RSp1222 nitrite reductase NADPH large subunit.
 
  
 0.967
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.941
Jden_2493
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
  
  0.918
Jden_2202
PFAM: Rieske [2Fe-2S] domain protein; KEGG: prw:PsycPRwf_1553 nitrite reductase (NAD(P)H), small subunit.
 
    0.898
Jden_0657
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: scl:sce0245 sirohydrochlorin cobaltochelatase.
 
  
 0.857
Jden_2361
PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: msl:Msil_3772 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
     0.801
Jden_2362
PFAM: major facilitator superfamily MFS_1; KEGG: bja:blr2806 nitrite extrusion protein.
 
  
 0.800
Your Current Organism:
Jonesia denitrificans
NCBI taxonomy Id: 471856
Other names: J. denitrificans DSM 20603, Jonesia denitrificans DSM 20603, Jonesia denitrificans str. DSM 20603, Jonesia denitrificans strain DSM 20603
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.