STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
ACU98033.1
PFAM: Dehydrogenase E1 component; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component.
 
 0.992
ACU95610.1
PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: succinate dehydrogenase, flavoprotein subunit, E. coli/mitochondrial subgroup; succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative/mitochondrial subgroup.
 0.987
ACU95609.1
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
 0.986
ACU97756.1
PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain; Pyridine nucleotide-disulphide oxidoreductase.
 0.984
ACU95612.1
PFAM: Succinate dehydrogenase cytochrome b subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit.
  
 
 0.983
ACU95611.1
PFAM: Succinate dehydrogenase cytochrome b subunit.
  
 
 0.982
ACU96105.1
2-oxoglutarate dehydrogenase E2 component; PFAM: e3 binding domain; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Biotin-requiring enzyme; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component).
 
 0.981
ACU97755.1
Succinate dehydrogenase subunit B; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
 
 0.980
ACU95414.1
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain.
  
 
 0.975
Your Current Organism:
Saccharomonospora viridis
NCBI taxonomy Id: 471857
Other names: S. viridis DSM 43017, Saccharomonospora viridis ATCC 15386, Saccharomonospora viridis DSM 43017, Saccharomonospora viridis NCIB 9602, Saccharomonospora viridis NRRL B-3044, Saccharomonospora viridis str. DSM 43017, Saccharomonospora viridis strain DSM 43017
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