node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACU95125.1 | ACU98222.1 | Svir_00350 | Svir_32510 | Anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | PFAM: chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | 0.999 |
ACU95125.1 | trpA | Svir_00350 | Svir_28090 | Anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.971 |
ACU95125.1 | trpB | Svir_00350 | Svir_28100 | Anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.984 |
ACU95125.1 | trpC | Svir_00350 | Svir_28110 | Anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.998 |
ACU95125.1 | trpD | Svir_00350 | Svir_10650 | Anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
ACU95125.1 | trpE | Svir_00350 | Svir_28130 | Anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.999 |
ACU97908.1 | ACU98157.1 | Svir_29300 | Svir_31840 | Phosphoserine phosphatase; PFAM: ACT domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. | L-threonine ammonia-lyase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | 0.909 |
ACU97908.1 | ilvA | Svir_29300 | Svir_23350 | Phosphoserine phosphatase; PFAM: ACT domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.909 |
ACU97908.1 | trpA | Svir_29300 | Svir_28090 | Phosphoserine phosphatase; PFAM: ACT domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.904 |
ACU97908.1 | trpB | Svir_29300 | Svir_28100 | Phosphoserine phosphatase; PFAM: ACT domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.921 |
ACU98157.1 | ACU97908.1 | Svir_31840 | Svir_29300 | L-threonine ammonia-lyase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | Phosphoserine phosphatase; PFAM: ACT domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. | 0.909 |
ACU98157.1 | ilvA | Svir_31840 | Svir_23350 | L-threonine ammonia-lyase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.920 |
ACU98157.1 | trpA | Svir_31840 | Svir_28090 | L-threonine ammonia-lyase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.918 |
ACU98157.1 | trpB | Svir_31840 | Svir_28100 | L-threonine ammonia-lyase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.927 |
ACU98222.1 | ACU95125.1 | Svir_32510 | Svir_00350 | PFAM: chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | Anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | 0.999 |
ACU98222.1 | trpA | Svir_32510 | Svir_28090 | PFAM: chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.921 |
ACU98222.1 | trpB | Svir_32510 | Svir_28100 | PFAM: chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.920 |
ACU98222.1 | trpC | Svir_32510 | Svir_28110 | PFAM: chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.981 |
ACU98222.1 | trpD | Svir_32510 | Svir_10650 | PFAM: chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.990 |
ACU98222.1 | trpE | Svir_32510 | Svir_28130 | PFAM: chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.851 |