STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (663 aa)    
Predicted Functional Partners:
ACU98324.1
PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
  
 0.963
ACU98346.1
PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.951
ACU95414.1
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain.
  
 
 0.942
ACU96022.1
PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family.
   
 0.939
ACU97816.1
PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family.
   
 0.939
ACU97041.1
acetyl-CoA acetyltransferase.
  
 
 0.930
ACU95624.1
PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
   
 0.929
ACU96809.1
PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
   
 0.929
ACU96823.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, N-terminal domain; Thiolase, C-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.929
ACU96917.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, N-terminal domain; Thiolase, C-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.929
Your Current Organism:
Saccharomonospora viridis
NCBI taxonomy Id: 471857
Other names: S. viridis DSM 43017, Saccharomonospora viridis ATCC 15386, Saccharomonospora viridis DSM 43017, Saccharomonospora viridis NCIB 9602, Saccharomonospora viridis NRRL B-3044, Saccharomonospora viridis str. DSM 43017, Saccharomonospora viridis strain DSM 43017
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.