STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recJKEGG: bth:BT3939 1.8e-290 recJ; single-stranded-DNA-specific exonuclease recJ K07462; COG: COG0608 Single-stranded DNA-specific exonuclease. (571 aa)    
Predicted Functional Partners:
EDV07748.1
KEGG: bfr:BF3933 1.1e-278 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.96.
    
 0.786
priA
Hypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.674
recQ-2
KEGG: bth:BT1848 3.4e-266 recQ; ATP-dependent DNA helicase recQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.96.
    
 0.672
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
  
 0.651
YaaA
COG: COG3022 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96; Belongs to the UPF0246 family.
       0.639
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.622
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.587
EDV03774.1
Putative Single-stranded DNA-binding protein; KEGG: shn:Shewana3_3590 4.3e-28 single-strand binding protein K00655; COG: COG0629 Single-stranded DNA-binding protein.
 
 
 0.581
DnaN
Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]
 
   
 0.525
EDV06541.1
comF family protein; KEGG: chu:CHU_3495 1.4e-31 purF; amidophosphoribosyltransferase K00764; COG: COG1040 Predicted amidophosphoribosyltransferases; Psort location: Cytoplasmic, score: 8.96.
 
   
 0.494
Your Current Organism:
Bacteroides intestinalis
NCBI taxonomy Id: 471870
Other names: B. intestinalis DSM 17393, Bacteroides intestinalis 341, Bacteroides intestinalis DSM 17393, Bacteroides intestinalis JCM 13265, Bacteroides intestinalis str. DSM 17393, Bacteroides intestinalis strain DSM 17393
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