node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DnaN | EDV03774.1 | BACINT_03456 | BACINT_02900 | Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] | Putative Single-stranded DNA-binding protein; KEGG: shn:Shewana3_3590 4.3e-28 single-strand binding protein K00655; COG: COG0629 Single-stranded DNA-binding protein. | 0.551 |
DnaN | EDV07748.1 | BACINT_03456 | BACINT_00146 | Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] | KEGG: bfr:BF3933 1.1e-278 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.96. | 0.570 |
DnaN | mutL | BACINT_03456 | BACINT_00026 | Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.910 |
DnaN | mutS | BACINT_03456 | BACINT_01203 | Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.832 |
DnaN | polA | BACINT_03456 | BACINT_01234 | Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.997 |
DnaN | priA | BACINT_03456 | BACINT_01737 | Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] | Hypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.544 |
DnaN | recJ | BACINT_03456 | BACINT_00147 | Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] | KEGG: bth:BT3939 1.8e-290 recJ; single-stranded-DNA-specific exonuclease recJ K07462; COG: COG0608 Single-stranded DNA-specific exonuclease. | 0.525 |
DnaN | recQ-2 | BACINT_03456 | BACINT_03226 | Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] | KEGG: bth:BT1848 3.4e-266 recQ; ATP-dependent DNA helicase recQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.96. | 0.570 |
EDV03774.1 | DnaN | BACINT_02900 | BACINT_03456 | Putative Single-stranded DNA-binding protein; KEGG: shn:Shewana3_3590 4.3e-28 single-strand binding protein K00655; COG: COG0629 Single-stranded DNA-binding protein. | Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] | 0.551 |
EDV03774.1 | EDV06541.1 | BACINT_02900 | BACINT_01628 | Putative Single-stranded DNA-binding protein; KEGG: shn:Shewana3_3590 4.3e-28 single-strand binding protein K00655; COG: COG0629 Single-stranded DNA-binding protein. | comF family protein; KEGG: chu:CHU_3495 1.4e-31 purF; amidophosphoribosyltransferase K00764; COG: COG1040 Predicted amidophosphoribosyltransferases; Psort location: Cytoplasmic, score: 8.96. | 0.416 |
EDV03774.1 | polA | BACINT_02900 | BACINT_01234 | Putative Single-stranded DNA-binding protein; KEGG: shn:Shewana3_3590 4.3e-28 single-strand binding protein K00655; COG: COG0629 Single-stranded DNA-binding protein. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.759 |
EDV03774.1 | priA | BACINT_02900 | BACINT_01737 | Putative Single-stranded DNA-binding protein; KEGG: shn:Shewana3_3590 4.3e-28 single-strand binding protein K00655; COG: COG0629 Single-stranded DNA-binding protein. | Hypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.861 |
EDV03774.1 | recJ | BACINT_02900 | BACINT_00147 | Putative Single-stranded DNA-binding protein; KEGG: shn:Shewana3_3590 4.3e-28 single-strand binding protein K00655; COG: COG0629 Single-stranded DNA-binding protein. | KEGG: bth:BT3939 1.8e-290 recJ; single-stranded-DNA-specific exonuclease recJ K07462; COG: COG0608 Single-stranded DNA-specific exonuclease. | 0.581 |
EDV06541.1 | EDV03774.1 | BACINT_01628 | BACINT_02900 | comF family protein; KEGG: chu:CHU_3495 1.4e-31 purF; amidophosphoribosyltransferase K00764; COG: COG1040 Predicted amidophosphoribosyltransferases; Psort location: Cytoplasmic, score: 8.96. | Putative Single-stranded DNA-binding protein; KEGG: shn:Shewana3_3590 4.3e-28 single-strand binding protein K00655; COG: COG0629 Single-stranded DNA-binding protein. | 0.416 |
EDV06541.1 | recJ | BACINT_01628 | BACINT_00147 | comF family protein; KEGG: chu:CHU_3495 1.4e-31 purF; amidophosphoribosyltransferase K00764; COG: COG1040 Predicted amidophosphoribosyltransferases; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT3939 1.8e-290 recJ; single-stranded-DNA-specific exonuclease recJ K07462; COG: COG0608 Single-stranded DNA-specific exonuclease. | 0.494 |
EDV07748.1 | DnaN | BACINT_00146 | BACINT_03456 | KEGG: bfr:BF3933 1.1e-278 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] | 0.570 |
EDV07748.1 | YaaA | BACINT_00146 | BACINT_00148 | KEGG: bfr:BF3933 1.1e-278 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.96. | COG: COG3022 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96; Belongs to the UPF0246 family. | 0.413 |
EDV07748.1 | mutL | BACINT_00146 | BACINT_00026 | KEGG: bfr:BF3933 1.1e-278 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.96. | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.564 |
EDV07748.1 | mutS | BACINT_00146 | BACINT_01203 | KEGG: bfr:BF3933 1.1e-278 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.96. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.473 |
EDV07748.1 | polA | BACINT_00146 | BACINT_01234 | KEGG: bfr:BF3933 1.1e-278 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.96. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.738 |