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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDV06246.1Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: bcl:ABC0632 7.9e-52 mannonate oxidoreductase; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score: 9.26. (269 aa)    
Predicted Functional Partners:
nuoC
Respiratory-chain NADH dehydrogenase, 49 Kd subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
 
 0.839
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.732
EDV06248.1
Glycosyl hydrolase family 2, sugar binding domain protein; KEGG: sal:Sala_1017 3.8e-84 beta-galactosidase K01190; COG: COG3250 Beta-galactosidase/beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
  
  
 0.564
fabD
[acyl-carrier-protein] S-malonyltransferase; KEGG: bfs:BF2352 1.5e-144 fabD, tfpA; malonyl CoA-acyl carrier protein transacylase K00645; COG: COG0331 (acyl-carrier-protein) S-malonyltransferase.
 
 
 0.544
EDV06247.1
Glycosyl hydrolase, family 88; KEGG: ret:RHE_PF00318 9.0e-52 putative glucoronyl hydrolase protein K01238; COG: NOG14425 non supervised orthologous group.
     
 0.527
uxaC
Glucuronate isomerase; KEGG: bth:BT0823 4.8e-251 uronate isomerase K01812; COG: COG1904 Glucuronate isomerase.
 
  
 0.522
EDV04390.1
Hydrogenase, Fe-only; KEGG: bth:BT0124 3.4e-298 NADH:ubiquinone oxidoreductase subunit K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain.
  
 
 0.503
EDV06221.1
KEGG: bca:BCE_3365 4.3e-37 protein-tyrosine phosphatase-like protein K01104; COG: COG2365 Protein tyrosine/serine phosphatase; Psort location: Cytoplasmic, score: 8.96.
  
 
 
 0.482
uxaC-2
Glucuronate isomerase; KEGG: bld:BLi03516 3.8e-107 uxaC; glucuronate isomerase; RBL02536 K01812; COG: COG1904 Glucuronate isomerase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.475
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.468
Your Current Organism:
Bacteroides intestinalis
NCBI taxonomy Id: 471870
Other names: B. intestinalis DSM 17393, Bacteroides intestinalis 341, Bacteroides intestinalis DSM 17393, Bacteroides intestinalis JCM 13265, Bacteroides intestinalis str. DSM 17393, Bacteroides intestinalis strain DSM 17393
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