Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nspCKEGG: hpa:HPAG1_0020 3.3e-78 carboxynorspermidine decarboxylase K01618; COG: COG0019 Diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 8.96. (366 aa)    
Predicted Functional Partners:
LYS1
KEGG: dvu:DVU0418 8.0e-139 lys1; saccharopine dehydrogenase K00290; COG: COG1748 Saccharopine dehydrogenase and related proteins.
 
 
 0.982
EDV03314.1
UvrD/REP helicase; KEGG: bth:BT0657 0. ATP-dependent DNA helicase K03657; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.96.
     
 0.662
EDV03315.1
Superoxide dismutase, Mn/Fe family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.586
EDV03048.1
Flavodoxin-like protein; KEGG: bth:BT0673 6.2e-68 NADP(H) oxidoreductase; COG: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).
    
  0.463
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.459
MetH
Hypothetical protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.458
hisI
Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; KEGG: bth:BT1377 1.1e-95 phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase K01496:K01523; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.97; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.437
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.415
guaA-2
GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 5.5e-218 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.415
ThrA
KEGG: bth:BT2403 0. homoserine dehydrogenase / aspartate kinase K00003:K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.403
Your Current Organism:
Bacteroides intestinalis
NCBI taxonomy Id: 471870
Other names: B. intestinalis DSM 17393, Bacteroides intestinalis 341, Bacteroides intestinalis DSM 17393, Bacteroides intestinalis JCM 13265, Bacteroides intestinalis str. DSM 17393, Bacteroides intestinalis strain DSM 17393
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