Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDV03316.1Thiamine monophosphate synthase/TENI; KEGG: chu:CHU_0246 1.1e-15 thiE; thiamine phosphate pyrophosphorylase K00788; COG: NOG25125 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.96. (202 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  0.988
thiD
KEGG: bth:BT0790 3.2e-80 phosphomethylpyrimidine kinase K00877:K00941; COG: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Psort location: Cytoplasmic, score: 8.96.
 
 0.979
thiL
Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
  
 
 0.930
EDV07667.1
Thiamine monophosphate synthase/TENI; KEGG: chu:CHU_0246 5.8e-17 thiE; thiamine phosphate pyrophosphorylase K00788; COG: NOG25125 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.96.
  
  
 
0.904
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
     
 0.902
rsgA-2
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
     
 0.902
EDV07122.1
KEGG: bfr:BF0480 4.3e-195 alkaline phosphatase III precursor K01077; COG: COG1785 Alkaline phosphatase; Psort location: Periplasmic, score: 10.00; Belongs to the alkaline phosphatase family.
    
  0.901
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.855
hydG
Iron-only hydrogenase maturation rSAM protein HydG; KEGG: mac:MA0154 2.8e-17 bioB; biotin synthase K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.672
EDV07478.1
Hypothetical protein; COG: NOG26548 non supervised orthologous group.
 
   
 0.584
Your Current Organism:
Bacteroides intestinalis
NCBI taxonomy Id: 471870
Other names: B. intestinalis DSM 17393, Bacteroides intestinalis 341, Bacteroides intestinalis DSM 17393, Bacteroides intestinalis JCM 13265, Bacteroides intestinalis str. DSM 17393, Bacteroides intestinalis strain DSM 17393
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