STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDV03320.1Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (303 aa)    
Predicted Functional Partners:
rumA
23S rRNA (uracil-5-)-methyltransferase RumA; KEGG: bfs:BF2568 1.4e-230 putative RNA methyltransferase K00599; COG: COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.96; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
  
  
 0.801
ppdK
KEGG: bth:BT0644 0. pyruvate phosphate dikinase K01006; COG: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Psort location: Cytoplasmic, score: 9.97; Belongs to the PEP-utilizing enzyme family.
     
 0.652
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 
 0.558
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 
 0.542
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
 
 0.542
EDV04817.1
RNA methyltransferase, TrmH family; KEGG: bth:BT4513 2.5e-119 putative rRNA methylase K00599; COG: COG0566 rRNA methylases; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.539
EDV04879.1
DEAD/DEAH box helicase; KEGG: eco:b0797 4.1e-103 rhlE; RNA helicase K01529; COG: COG0513 Superfamily II DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.96; Belongs to the DEAD box helicase family.
 
 0.536
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 
 0.525
EDV03441.1
DEAD/DEAH box helicase; KEGG: eci:UTI89_C1614 1.3e-51 dbpA; ATP-independent RNA helicase DbpA K05591; COG: COG0513 Superfamily II DNA and RNA helicases.
 
 0.521
prfB
Putative peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
 
 
 0.511
Your Current Organism:
Bacteroides intestinalis
NCBI taxonomy Id: 471870
Other names: B. intestinalis DSM 17393, Bacteroides intestinalis 341, Bacteroides intestinalis DSM 17393, Bacteroides intestinalis JCM 13265, Bacteroides intestinalis str. DSM 17393, Bacteroides intestinalis strain DSM 17393
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