| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDV02909.1 | EDV04204.1 | BACINT_02020 | BACINT_03337 | KEGG: bth:BT0870 8.5e-174 8-amino-7-oxononanoate synthase K00652; COG: COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; Psort location: Cytoplasmic, score: 8.96. | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | 0.903 |
| EDV02909.1 | bioA | BACINT_02020 | BACINT_03335 | KEGG: bth:BT0870 8.5e-174 8-amino-7-oxononanoate synthase K00652; COG: COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; Psort location: Cytoplasmic, score: 8.96. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.957 |
| EDV02909.1 | bioD | BACINT_02020 | BACINT_03339 | KEGG: bth:BT0870 8.5e-174 8-amino-7-oxononanoate synthase K00652; COG: COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; Psort location: Cytoplasmic, score: 8.96. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.750 |
| EDV02909.1 | bioF | BACINT_02020 | BACINT_03336 | KEGG: bth:BT0870 8.5e-174 8-amino-7-oxononanoate synthase K00652; COG: COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT1443 4.1e-151 8-amino-7-oxononanoate synthase K00652; COG: COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.919 |
| EDV03493.1 | EDV04204.1 | BACINT_02615 | BACINT_03337 | Hypothetical protein; COG: NOG17489 non supervised orthologous group. | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | 0.544 |
| EDV04201.1 | EDV04204.1 | BACINT_03334 | BACINT_03337 | Hypothetical protein; KEGG: bth:BT1442 1.3e-05 adenosylmethionine-8-amino-7-oxononanoate aminotransferase. | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | 0.573 |
| EDV04201.1 | EDV04207.1 | BACINT_03334 | BACINT_03340 | Hypothetical protein; KEGG: bth:BT1442 1.3e-05 adenosylmethionine-8-amino-7-oxononanoate aminotransferase. | Glycosyltransferase, group 2 family protein; KEGG: chu:CHU_2182 9.6e-10 ycdQ; b-glycosyltransferase-related protein, glycosyltransferase family 2 protein K00754; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: CytoplasmicMembrane, score: 9.46. | 0.466 |
| EDV04201.1 | bioA | BACINT_03334 | BACINT_03335 | Hypothetical protein; KEGG: bth:BT1442 1.3e-05 adenosylmethionine-8-amino-7-oxononanoate aminotransferase. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.821 |
| EDV04201.1 | bioC | BACINT_03334 | BACINT_03338 | Hypothetical protein; KEGG: bth:BT1442 1.3e-05 adenosylmethionine-8-amino-7-oxononanoate aminotransferase. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.573 |
| EDV04201.1 | bioD | BACINT_03334 | BACINT_03339 | Hypothetical protein; KEGG: bth:BT1442 1.3e-05 adenosylmethionine-8-amino-7-oxononanoate aminotransferase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.649 |
| EDV04201.1 | bioF | BACINT_03334 | BACINT_03336 | Hypothetical protein; KEGG: bth:BT1442 1.3e-05 adenosylmethionine-8-amino-7-oxononanoate aminotransferase. | KEGG: bth:BT1443 4.1e-151 8-amino-7-oxononanoate synthase K00652; COG: COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.821 |
| EDV04204.1 | EDV02909.1 | BACINT_03337 | BACINT_02020 | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT0870 8.5e-174 8-amino-7-oxononanoate synthase K00652; COG: COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; Psort location: Cytoplasmic, score: 8.96. | 0.903 |
| EDV04204.1 | EDV03493.1 | BACINT_03337 | BACINT_02615 | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; COG: NOG17489 non supervised orthologous group. | 0.544 |
| EDV04204.1 | EDV04201.1 | BACINT_03337 | BACINT_03334 | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; KEGG: bth:BT1442 1.3e-05 adenosylmethionine-8-amino-7-oxononanoate aminotransferase. | 0.573 |
| EDV04204.1 | EDV04207.1 | BACINT_03337 | BACINT_03340 | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | Glycosyltransferase, group 2 family protein; KEGG: chu:CHU_2182 9.6e-10 ycdQ; b-glycosyltransferase-related protein, glycosyltransferase family 2 protein K00754; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: CytoplasmicMembrane, score: 9.46. | 0.673 |
| EDV04204.1 | EDV05004.1 | BACINT_03337 | BACINT_04147 | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; COG: NOG19100 non supervised orthologous group. | 0.443 |
| EDV04204.1 | EDV05293.1 | BACINT_03337 | BACINT_04438 | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; KEGG: bfs:BF0894 1.1e-139 putative enoyl-[acyl-carrier-protein] reductase [NADH] K00208; COG: COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH). | 0.913 |
| EDV04204.1 | bioA | BACINT_03337 | BACINT_03335 | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.866 |
| EDV04204.1 | bioC | BACINT_03337 | BACINT_03338 | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.989 |
| EDV04204.1 | bioD | BACINT_03337 | BACINT_03339 | COG: COG2830 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.96. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.958 |