STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDT03901.1tRNA A37 threonylcarbamoyladenosine dehydratase. (258 aa)    
Predicted Functional Partners:
SDS93645.1
Adenylyltransferase and sulfurtransferase.
 
 
0.797
thiI
Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 
 0.728
SDS74098.1
Sulfur carrier protein.
   
  0.718
SDS13692.1
Molybdopterin synthase sulfur carrier subunit.
    
  0.677
SDS33075.1
Cysteine desulfurase.
    
 0.671
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
  0.660
rlmF
23S rRNA (adenine1618-N6)-methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA.
       0.534
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
  
    0.447
SDT03781.1
23S rRNA (guanine745-N1)-methyltransferase.
       0.440
SDR82551.1
Cysteine desulfuration protein SufE.
   
 
 0.430
Your Current Organism:
Pseudomonas sabulinigri
NCBI taxonomy Id: 472181
Other names: JCM 14963, KCTC 22137, P. sabulinigri, Pseudomonas sabulinigri Kim et al. 2009, Pseudomonas sp. J64, strain J64
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