| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LO55_1057 | LO55_4791 | LO55_1057 | LO55_4791 | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.940 |
| LO55_1057 | bioF | LO55_1057 | LO55_1505 | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.734 |
| LO55_1057 | cobA | LO55_1057 | LO55_4992 | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.965 |
| LO55_1057 | hemA | LO55_1057 | LO55_1372 | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.873 |
| LO55_1057 | hemC | LO55_1057 | LO55_4792 | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
| LO55_1057 | hemE | LO55_1057 | LO55_1578 | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.921 |
| LO55_1057 | hemL | LO55_1057 | LO55_2086 | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | hemL: glutamate-1-semialdehyde-2,1-aminomutase. | 0.995 |
| LO55_1057 | kbl | LO55_1057 | LO55_4299 | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.734 |
| LO55_2087 | hemL | LO55_2087 | LO55_2086 | Phosphomethylpyrimidine kinase family protein. | hemL: glutamate-1-semialdehyde-2,1-aminomutase. | 0.767 |
| LO55_2087 | thiE | LO55_2087 | LO55_623 | Phosphomethylpyrimidine kinase family protein. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.997 |
| LO55_4791 | LO55_1057 | LO55_4791 | LO55_1057 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | 0.940 |
| LO55_4791 | cobA | LO55_4791 | LO55_4992 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.890 |
| LO55_4791 | hemA | LO55_4791 | LO55_1372 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.793 |
| LO55_4791 | hemC | LO55_4791 | LO55_4792 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
| LO55_4791 | hemE | LO55_4791 | LO55_1578 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.848 |
| LO55_4791 | hemL | LO55_4791 | LO55_2086 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | hemL: glutamate-1-semialdehyde-2,1-aminomutase. | 0.763 |
| bioF | LO55_1057 | LO55_1505 | LO55_1057 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | 0.734 |
| bioF | hemL | LO55_1505 | LO55_2086 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | hemL: glutamate-1-semialdehyde-2,1-aminomutase. | 0.704 |
| cobA | LO55_1057 | LO55_4992 | LO55_1057 | cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family. | 0.965 |
| cobA | LO55_4791 | LO55_4992 | LO55_4791 | cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.890 |