| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LO55_2060 | LO55_2095 | LO55_2060 | LO55_2095 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.945 |
| LO55_2060 | LO55_2097 | LO55_2060 | LO55_2097 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Phosphoribosyl transferase domain protein. | 0.662 |
| LO55_2060 | LO55_728 | LO55_2060 | LO55_728 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.821 |
| LO55_2060 | dnaN | LO55_2060 | LO55_1675 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.871 |
| LO55_2060 | pyrB | LO55_2060 | LO55_2098 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.401 |
| LO55_2060 | tdk | LO55_2060 | LO55_4450 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidine kinase family protein. | 0.624 |
| LO55_2060 | thyA | LO55_2060 | LO55_4351 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.891 |
| LO55_2095 | LO55_2060 | LO55_2095 | LO55_2060 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.945 |
| LO55_2095 | LO55_2096 | LO55_2095 | LO55_2096 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.968 |
| LO55_2095 | LO55_2097 | LO55_2095 | LO55_2097 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Phosphoribosyl transferase domain protein. | 0.729 |
| LO55_2095 | LO55_2894 | LO55_2095 | LO55_2894 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | AAA domain protein. | 0.888 |
| LO55_2095 | LO55_728 | LO55_2095 | LO55_728 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.945 |
| LO55_2095 | dnaN | LO55_2095 | LO55_1675 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.840 |
| LO55_2095 | pyrB | LO55_2095 | LO55_2098 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.827 |
| LO55_2095 | pyrC-2 | LO55_2095 | LO55_2099 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Dihydroorotase; Multifunctional complex type domain protein; pyrC_multi: dihydroorotase, multifunctional complex type domain protein. | 0.736 |
| LO55_2095 | tdk | LO55_2095 | LO55_4450 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Thymidine kinase family protein. | 0.682 |
| LO55_2095 | thyA | LO55_2095 | LO55_4351 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.695 |
| LO55_2096 | LO55_2095 | LO55_2096 | LO55_2095 | Hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.968 |
| LO55_2096 | LO55_2097 | LO55_2096 | LO55_2097 | Hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Phosphoribosyl transferase domain protein. | 0.794 |
| LO55_2096 | pyrB | LO55_2096 | LO55_2098 | Hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.863 |
