Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LO55_2245cys/Met metabolism PLP-dependent enzyme family protein. (417 aa)    
Predicted Functional Partners:
iscU
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 0.992
LO55_1157
Aminotransferase class-V family protein.
 
  
 0.878
LO55_5125
GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.828
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
    
 0.811
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.789
LO55_2754
Pyridine nucleotide-disulfide oxidoreductase family protein.
  
 
  0.777
LO55_2223
Catalase family protein; Serves to protect cells from the toxic effects of hydrogen peroxide.
    
 0.753
trxB
TRX_reduct: thioredoxin-disulfide reductase.
  
 
  0.750
LO55_685
Glutamine amidotransferases class-II family protein.
  
 
 0.726
LO55_982
endonuclease/Exonuclease/phosphatase family protein.
   
   0.696
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
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