| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LO55_137 | LO55_218 | LO55_137 | LO55_218 | 2Fe-2S iron-sulfur cluster binding domain protein. | D-ala D-ala ligase family protein. | 0.928 |
| LO55_137 | carA | LO55_137 | LO55_4648 | 2Fe-2S iron-sulfur cluster binding domain protein. | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.965 |
| LO55_137 | carB | LO55_137 | LO55_4647 | 2Fe-2S iron-sulfur cluster binding domain protein. | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.928 |
| LO55_137 | guaA | LO55_137 | LO55_3626 | 2Fe-2S iron-sulfur cluster binding domain protein. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.488 |
| LO55_137 | pyrB | LO55_137 | LO55_2098 | 2Fe-2S iron-sulfur cluster binding domain protein. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.956 |
| LO55_137 | pyrC | LO55_137 | LO55_1732 | 2Fe-2S iron-sulfur cluster binding domain protein. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.625 |
| LO55_137 | pyrC-2 | LO55_137 | LO55_2099 | 2Fe-2S iron-sulfur cluster binding domain protein. | Dihydroorotase; Multifunctional complex type domain protein; pyrC_multi: dihydroorotase, multifunctional complex type domain protein. | 0.957 |
| LO55_137 | pyrD | LO55_137 | LO55_2399 | 2Fe-2S iron-sulfur cluster binding domain protein. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.994 |
| LO55_137 | pyrE | LO55_137 | LO55_711 | 2Fe-2S iron-sulfur cluster binding domain protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.973 |
| LO55_137 | pyrF | LO55_137 | LO55_144 | 2Fe-2S iron-sulfur cluster binding domain protein. | pyrF_sub2: orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.973 |
| LO55_218 | LO55_137 | LO55_218 | LO55_137 | D-ala D-ala ligase family protein. | 2Fe-2S iron-sulfur cluster binding domain protein. | 0.928 |
| LO55_218 | carA | LO55_218 | LO55_4648 | D-ala D-ala ligase family protein. | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.985 |
| LO55_218 | guaA | LO55_218 | LO55_3626 | D-ala D-ala ligase family protein. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.807 |
| LO55_218 | pyrB | LO55_218 | LO55_2098 | D-ala D-ala ligase family protein. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.928 |
| LO55_218 | pyrC | LO55_218 | LO55_1732 | D-ala D-ala ligase family protein. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.835 |
| LO55_218 | pyrC-2 | LO55_218 | LO55_2099 | D-ala D-ala ligase family protein. | Dihydroorotase; Multifunctional complex type domain protein; pyrC_multi: dihydroorotase, multifunctional complex type domain protein. | 0.888 |
| LO55_218 | pyrD | LO55_218 | LO55_2399 | D-ala D-ala ligase family protein. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.948 |
| LO55_218 | pyrE | LO55_218 | LO55_711 | D-ala D-ala ligase family protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.911 |
| LO55_218 | pyrF | LO55_218 | LO55_144 | D-ala D-ala ligase family protein. | pyrF_sub2: orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.889 |
| carA | LO55_137 | LO55_4648 | LO55_137 | CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 2Fe-2S iron-sulfur cluster binding domain protein. | 0.965 |
