| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LO55_1359 | LO55_2908 | LO55_1359 | LO55_2908 | NADH:flavin oxidoreductase / NADH oxidase family protein. | Beta-eliminating lyase family protein. | 0.774 |
| LO55_1359 | fdx | LO55_1359 | LO55_2906 | NADH:flavin oxidoreductase / NADH oxidase family protein. | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system. | 0.849 |
| LO55_1359 | gcvP | LO55_1359 | LO55_3553 | NADH:flavin oxidoreductase / NADH oxidase family protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.896 |
| LO55_1359 | glyA | LO55_1359 | LO55_4915 | NADH:flavin oxidoreductase / NADH oxidase family protein. | Aminotransferase class I and II family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.789 |
| LO55_2907 | LO55_2908 | LO55_2907 | LO55_2908 | Methyltransferase domain protein. | Beta-eliminating lyase family protein. | 0.789 |
| LO55_2907 | LO55_2909 | LO55_2907 | LO55_2909 | Methyltransferase domain protein. | S4 domain protein. | 0.789 |
| LO55_2907 | fdx | LO55_2907 | LO55_2906 | Methyltransferase domain protein. | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system. | 0.773 |
| LO55_2908 | LO55_1359 | LO55_2908 | LO55_1359 | Beta-eliminating lyase family protein. | NADH:flavin oxidoreductase / NADH oxidase family protein. | 0.774 |
| LO55_2908 | LO55_2907 | LO55_2908 | LO55_2907 | Beta-eliminating lyase family protein. | Methyltransferase domain protein. | 0.789 |
| LO55_2908 | LO55_2909 | LO55_2908 | LO55_2909 | Beta-eliminating lyase family protein. | S4 domain protein. | 0.789 |
| LO55_2908 | LO55_3053 | LO55_2908 | LO55_3053 | Beta-eliminating lyase family protein. | Pyridoxal-phosphate dependent enzyme family protein. | 0.748 |
| LO55_2908 | LO55_4916 | LO55_2908 | LO55_4916 | Beta-eliminating lyase family protein. | Short chain dehydrogenase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.820 |
| LO55_2908 | fdx | LO55_2908 | LO55_2906 | Beta-eliminating lyase family protein. | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system. | 0.773 |
| LO55_2908 | gcvP | LO55_2908 | LO55_3553 | Beta-eliminating lyase family protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.917 |
| LO55_2908 | glyA | LO55_2908 | LO55_4915 | Beta-eliminating lyase family protein. | Aminotransferase class I and II family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.921 |
| LO55_2908 | ilvA | LO55_2908 | LO55_1005 | Beta-eliminating lyase family protein. | Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.748 |
| LO55_2908 | thrC | LO55_2908 | LO55_4296 | Beta-eliminating lyase family protein. | thrC: threonine synthase. | 0.906 |
| LO55_2909 | LO55_2907 | LO55_2909 | LO55_2907 | S4 domain protein. | Methyltransferase domain protein. | 0.789 |
| LO55_2909 | LO55_2908 | LO55_2909 | LO55_2908 | S4 domain protein. | Beta-eliminating lyase family protein. | 0.789 |
| LO55_2909 | fdx | LO55_2909 | LO55_2906 | S4 domain protein. | Fdx_isc: ferredoxin, 2Fe-2S type, ISC system. | 0.773 |
