Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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sbcDExonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (423 aa)    
Predicted Functional Partners:
LO55_3165
AAA domain protein.
 
 0.999
LO55_1788
Hypothetical protein; 5'-3' exonuclease, C-terminal SAM fold family protein.
  
 0.955
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.955
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.903
recQ
recQ: ATP-dependent DNA helicase RecQ.
  
 0.879
LO55_2703
recQ_fam: ATP-dependent DNA helicase, RecQ family protein.
  
 0.879
holB
holB: DNA polymerase III, delta' subunit.
  
 0.843
LO55_3433
Eukaryotic DNA topoisomerase I, catalytic core family protein.
   
 
 0.821
LO55_2822
DEAD_2 family protein.
   
 0.813
LO55_4609
DEAD_2 family protein.
   
 0.813
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
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