STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceAIsocit_lyase: isocitrate lyase. (432 aa)    
Predicted Functional Partners:
aceB
malate_syn_A: malate synthase A; Belongs to the malate synthase family.
 
 0.999
LO55_1932
Malic enzyme, NAD binding domain protein; Belongs to the malic enzymes family.
   
 
 0.955
maeB
NADP-dependent malic enzyme.
   
 
 0.955
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
  
 0.890
ackA-2
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
  
 0.890
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
 
 0.844
LO55_3109
Phosphate acetyl/butaryl transferase family protein.
   
 
 0.832
LO55_4737
Phosphate acetyl/butaryl transferase family protein.
   
 
 0.832
LO55_236
Hydrolyase, tartrate alpha subunit/fumarate, Fe-S type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.792
LO55_1001
4Fe-4S dicluster domain protein.
     
 0.758
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.