Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bkdA12-oxoisovalerate dehydrogenase subunit alpha. (410 aa)    
Predicted Functional Partners:
bkdA2
2-oxoisovalerate dehydrogenase subunit beta.
 0.999
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 
 0.998
lpdA
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 0.996
lpdA-3
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 
 0.995
aceF
Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.979
lpdA-2
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 
 0.972
LO55_1581
Pyridine nucleotide-disulfide oxidoreductase family protein.
 
 
 0.965
sucB
Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.958
LO55_1932
Malic enzyme, NAD binding domain protein; Belongs to the malic enzymes family.
  
 
 0.895
maeB
NADP-dependent malic enzyme.
  
 
 0.895
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
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