STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (435 aa)    
Predicted Functional Partners:
hppD
4HPPD: 4-hydroxyphenylpyruvate dioxygenase.
 
 0.997
maiA
maiA: maleylacetoacetate isomerase.
 
 
 0.980
LO55_2560
Hypothetical protein.
  
 0.966
LO55_2436
Fumarylacetoacetate (FAA) hydrolase family protein.
 
  
 0.788
LO55_2896
Fumarylacetoacetate (FAA) hydrolase family protein.
 
  
 0.786
LO55_4958
Pterin 4 alpha carbinolamine dehydratase family protein.
  
  
 0.760
LO55_4010
Fumarylacetoacetate (FAA) hydrolase family protein.
  
  
 0.733
LO55_169
Fumarylacetoacetate (FAA) hydrolase family protein.
  
  
 0.716
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
     
 0.694
LO55_1997
Fumarylacetoacetate (FAA) hydrolase family protein.
  
  
 0.646
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.