Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (435 aa)    
Predicted Functional Partners:
hppD
4HPPD: 4-hydroxyphenylpyruvate dioxygenase.
 
 0.997
maiA
maiA: maleylacetoacetate isomerase.
 
 
 0.993
LO55_2560
Hypothetical protein.
  
 0.903
LO55_4958
Pterin 4 alpha carbinolamine dehydratase family protein.
  
  
 0.726
LO55_2436
Fumarylacetoacetate (FAA) hydrolase family protein.
 
  
 0.720
LO55_2896
Fumarylacetoacetate (FAA) hydrolase family protein.
 
  
 0.717
LO55_4010
Fumarylacetoacetate (FAA) hydrolase family protein.
  
  
 0.648
LO55_169
Fumarylacetoacetate (FAA) hydrolase family protein.
  
  
 0.636
LO55_2855
Aminotransferase class I and II family protein.
  
  
 0.592
LO55_1508
Carboxyl transferase domain protein.
 
  
 0.576
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
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