STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hppD4HPPD: 4-hydroxyphenylpyruvate dioxygenase. (364 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
 0.997
LO55_2855
Aminotransferase class I and II family protein.
  
 
 0.929
LO55_1508
Carboxyl transferase domain protein.
 
 
 0.914
LO55_4958
Pterin 4 alpha carbinolamine dehydratase family protein.
  
  
 0.910
mdcE
Malonate_gamma: biotin-independent malonate decarboxylase, gamma subunit.
  
 
 0.894
maiA
maiA: maleylacetoacetate isomerase.
 
  
 0.892
LO55_2896
Fumarylacetoacetate (FAA) hydrolase family protein.
 
  
 0.853
LO55_2436
Fumarylacetoacetate (FAA) hydrolase family protein.
 
  
 0.852
icmF
Hypothetical protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
 0.840
uca
Urea_carbox: urea carboxylase.
  
 
 0.786
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.