| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LO55_4297 | LO55_5088 | LO55_4297 | LO55_5088 | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | CBS domain protein. | 0.889 |
| LO55_4297 | glyA | LO55_4297 | LO55_4915 | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Aminotransferase class I and II family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.959 |
| LO55_4297 | metX | LO55_4297 | LO55_717 | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.855 |
| LO55_4297 | pssA | LO55_4297 | LO55_1684 | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.851 |
| LO55_4297 | pssA-2 | LO55_4297 | LO55_2925 | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.851 |
| LO55_4297 | serB | LO55_4297 | LO55_4404 | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | serB: phosphoserine phosphatase SerB. | 0.876 |
| LO55_4297 | serC | LO55_4297 | LO55_48 | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.753 |
| LO55_4297 | trpA | LO55_4297 | LO55_2723 | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | trpA: tryptophan synthase, alpha subunit; Belongs to the TrpA family. | 0.882 |
| LO55_4297 | trpB | LO55_4297 | LO55_2722 | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.852 |
| LO55_5088 | LO55_4297 | LO55_5088 | LO55_4297 | CBS domain protein. | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.889 |
| LO55_5088 | glyA | LO55_5088 | LO55_4915 | CBS domain protein. | Aminotransferase class I and II family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
| LO55_5088 | metX | LO55_5088 | LO55_717 | CBS domain protein. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.906 |
| LO55_5088 | pssA | LO55_5088 | LO55_1684 | CBS domain protein. | pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.851 |
| LO55_5088 | pssA-2 | LO55_5088 | LO55_2925 | CBS domain protein. | pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.851 |
| LO55_5088 | serB | LO55_5088 | LO55_4404 | CBS domain protein. | serB: phosphoserine phosphatase SerB. | 0.886 |
| LO55_5088 | serC | LO55_5088 | LO55_48 | CBS domain protein. | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.784 |
| LO55_5088 | trpA | LO55_5088 | LO55_2723 | CBS domain protein. | trpA: tryptophan synthase, alpha subunit; Belongs to the TrpA family. | 0.894 |
| LO55_5088 | trpB | LO55_5088 | LO55_2722 | CBS domain protein. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.872 |
| glyA | LO55_4297 | LO55_4915 | LO55_4297 | Aminotransferase class I and II family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sda_mono: L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.959 |
| glyA | LO55_5088 | LO55_4915 | LO55_5088 | Aminotransferase class I and II family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | CBS domain protein. | 0.923 |
