Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LO55_4632mmgE/PrpD family protein. (457 aa)    
Predicted Functional Partners:
LO55_4635
Hypothetical protein; N-terminal half of MaoC dehydratase family protein.
 
  
 0.971
LO55_4630
hpcH/HpaI aldolase/citrate lyase family protein; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.952
LO55_236
Hydrolyase, tartrate alpha subunit/fumarate, Fe-S type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.939
LO55_4633
coA-transferase III family protein; Belongs to the CoA-transferase III family.
 
 
  0.916
gltA
cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 
 0.912
LO55_5080
cit_synth_II: 2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family.
  
 
 0.912
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
  
 0.901
LO55_4634
Hypothetical protein; acyl-CoA dehydrogenase, N-terminal domain protein.
 
  
 0.872
LO55_1548
Glutamine amidotransferases class-II family protein.
    
 0.868
prpF
prpF: putative AcnD-accessory protein PrpF.
 
 
 0.821
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
Server load: low (16%) [HD]