STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LO55_4635Hypothetical protein; N-terminal half of MaoC dehydratase family protein. (286 aa)    
Predicted Functional Partners:
LO55_4632
mmgE/PrpD family protein.
 
  
 0.977
LO55_4630
hpcH/HpaI aldolase/citrate lyase family protein; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.962
LO55_4634
Hypothetical protein; acyl-CoA dehydrogenase, N-terminal domain protein.
 
     0.905
LO55_2774
hpcH/HpaI aldolase/citrate lyase family protein; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.866
LO55_4633
coA-transferase III family protein; Belongs to the CoA-transferase III family.
 
 
 0.864
LO55_1103
C-C Bond Lyase of the TIM-Barrel fold family protein.
  
 
 0.823
sucD
succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
  0.609
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
  0.608
LO55_4636
Bacterial regulatory helix-turn-helix, lysR family protein; Belongs to the LysR transcriptional regulatory family.
 
     0.579
LO55_4444
maoC like domain protein.
  
  
 0.578
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.