Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
LO55_4869Alpha/beta hydrolase fold family protein; Belongs to the type-B carboxylesterase/lipase family. (477 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.847
lpdA
lipoamide_DH: dihydrolipoyl dehydrogenase.
   
 0.717
LO55_1629
Hypothetical protein.
    
 0.711
LO55_3165
AAA domain protein.
    
   0.697
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
   0.668
LO55_4796
3'-5' exonuclease family protein.
    
  0.660
aceF
Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
  0.632
sucB
Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
   
  0.632
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
   
  0.632
LO55_4868
Bacterial regulatory helix-turn-helix, lysR family protein; Belongs to the LysR transcriptional regulatory family.
       0.596
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
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