Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobD-2cobD/Cbib family protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (319 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 
 0.912
LO55_765
L_thr_O3P_dcar: threonine-phosphate decarboxylase.
 
  
 0.907
LO55_763
Cobinamide kinase / cobinamide phosphate guanyltransferase family protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
 
 
 0.904
cobO
cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
  
 0.885
LO55_585
ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family.
 
  
 0.856
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
  
 
0.844
LO55_4790
hemX family protein.
 
   
 0.751
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.720
LO55_3560
Hypothetical protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.695
LO55_315
Hypothetical protein.
  
     0.687
Your Current Organism:
Massilia timonae
NCBI taxonomy Id: 47229
Other names: CCUG 45783, CIP 105350, Janthinobacterium sp. R2-11, M. timonae, Massilia timonae La Scola et al. 2000 emend. Lindquist et al. 2003, Timone isolate, strain UR/MT95
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