| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LO55_3128 | LO55_959 | LO55_3128 | LO55_959 | Hypothetical protein; acyl-CoA dehydrogenase, N-terminal domain protein. | Methyltransferase small domain protein. | 0.641 |
| LO55_3128 | gcvP | LO55_3128 | LO55_3553 | Hypothetical protein; acyl-CoA dehydrogenase, N-terminal domain protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.552 |
| LO55_3128 | glyA | LO55_3128 | LO55_4915 | Hypothetical protein; acyl-CoA dehydrogenase, N-terminal domain protein. | Aminotransferase class I and II family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.598 |
| LO55_3128 | rfbC | LO55_3128 | LO55_2454 | Hypothetical protein; acyl-CoA dehydrogenase, N-terminal domain protein. | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | 0.428 |
| LO55_3869 | LO55_959 | LO55_3869 | LO55_959 | FAD dependent oxidoreductase family protein. | Methyltransferase small domain protein. | 0.622 |
| LO55_3869 | pyrB | LO55_3869 | LO55_2098 | FAD dependent oxidoreductase family protein. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.554 |
| LO55_4169 | LO55_959 | LO55_4169 | LO55_959 | Zinc-binding dehydrogenase family protein. | Methyltransferase small domain protein. | 0.450 |
| LO55_4169 | gcvP | LO55_4169 | LO55_3553 | Zinc-binding dehydrogenase family protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.445 |
| LO55_4222 | LO55_959 | LO55_4222 | LO55_959 | Peptidase U32 family protein. | Methyltransferase small domain protein. | 0.853 |
| LO55_958 | LO55_959 | LO55_958 | LO55_959 | gyrI-like small molecule binding domain protein. | Methyltransferase small domain protein. | 0.543 |
| LO55_959 | LO55_3128 | LO55_959 | LO55_3128 | Methyltransferase small domain protein. | Hypothetical protein; acyl-CoA dehydrogenase, N-terminal domain protein. | 0.641 |
| LO55_959 | LO55_3869 | LO55_959 | LO55_3869 | Methyltransferase small domain protein. | FAD dependent oxidoreductase family protein. | 0.622 |
| LO55_959 | LO55_4169 | LO55_959 | LO55_4169 | Methyltransferase small domain protein. | Zinc-binding dehydrogenase family protein. | 0.450 |
| LO55_959 | LO55_4222 | LO55_959 | LO55_4222 | Methyltransferase small domain protein. | Peptidase U32 family protein. | 0.853 |
| LO55_959 | LO55_958 | LO55_959 | LO55_958 | Methyltransferase small domain protein. | gyrI-like small molecule binding domain protein. | 0.543 |
| LO55_959 | LO55_960 | LO55_959 | LO55_960 | Methyltransferase small domain protein. | Hypothetical protein. | 0.503 |
| LO55_959 | gcvP | LO55_959 | LO55_3553 | Methyltransferase small domain protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.851 |
| LO55_959 | glyA | LO55_959 | LO55_4915 | Methyltransferase small domain protein. | Aminotransferase class I and II family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.482 |
| LO55_959 | pyrB | LO55_959 | LO55_2098 | Methyltransferase small domain protein. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.451 |
| LO55_959 | rfbC | LO55_959 | LO55_2454 | Methyltransferase small domain protein. | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | 0.589 |