node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCA_001743465_00795 | HA41_02810 | GCA_001743465_00795 | GCA_001743465_01111 | Unannotated protein. | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.952 |
GCA_001743465_00795 | HA41_02815 | GCA_001743465_00795 | GCA_001743465_01110 | Unannotated protein. | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.956 |
GCA_001743465_00795 | cobB | GCA_001743465_00795 | GCA_001743465_01392 | Unannotated protein. | Unannotated protein; Belongs to the sirtuin family. Class III subfamily. | 0.966 |
GCA_001743465_00795 | nadD | GCA_001743465_00795 | GCA_001743465_00316 | Unannotated protein. | Unannotated protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.973 |
GCA_001743465_00795 | nadK | GCA_001743465_00795 | GCA_001743465_03789 | Unannotated protein. | Unannotated protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.967 |
GCA_001743465_00795 | sthA | GCA_001743465_00795 | GCA_001743465_03255 | Unannotated protein. | Unannotated protein; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.952 |
GCA_001743465_03171 | HA41_02810 | GCA_001743465_03171 | GCA_001743465_01111 | Unannotated protein. | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.724 |
HA41_02810 | GCA_001743465_00795 | GCA_001743465_01111 | GCA_001743465_00795 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | Unannotated protein. | 0.952 |
HA41_02810 | GCA_001743465_03171 | GCA_001743465_01111 | GCA_001743465_03171 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | Unannotated protein. | 0.724 |
HA41_02810 | HA41_02815 | GCA_001743465_01111 | GCA_001743465_01110 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
HA41_02810 | HA41_10870 | GCA_001743465_01111 | GCA_001743465_04412 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | Unannotated protein. | 0.952 |
HA41_02810 | HA41_11235 | GCA_001743465_01111 | GCA_001743465_04347 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | Unannotated protein. | 0.479 |
HA41_02810 | cobB | GCA_001743465_01111 | GCA_001743465_01392 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | Unannotated protein; Belongs to the sirtuin family. Class III subfamily. | 0.961 |
HA41_02810 | ilvC | GCA_001743465_01111 | GCA_001743465_01164 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.669 |
HA41_02810 | nadD | GCA_001743465_01111 | GCA_001743465_00316 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | Unannotated protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.957 |
HA41_02810 | nadK | GCA_001743465_01111 | GCA_001743465_03789 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | Unannotated protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.964 |
HA41_02810 | sthA | GCA_001743465_01111 | GCA_001743465_03255 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | Unannotated protein; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.965 |
HA41_02815 | GCA_001743465_00795 | GCA_001743465_01110 | GCA_001743465_00795 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Unannotated protein. | 0.956 |
HA41_02815 | HA41_02810 | GCA_001743465_01110 | GCA_001743465_01111 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.999 |
HA41_02815 | HA41_10870 | GCA_001743465_01110 | GCA_001743465_04412 | Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Unannotated protein. | 0.953 |