node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCA_001743465_03426 | HA41_07500 | GCA_001743465_03426 | GCA_001743465_00777 | Unannotated protein. | Unannotated protein; Belongs to the precorrin methyltransferase family. | 0.997 |
GCA_001743465_03426 | HA41_10510 | GCA_001743465_03426 | GCA_001743465_03427 | Unannotated protein. | Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.999 |
GCA_001743465_03426 | HA41_15145 | GCA_001743465_03426 | GCA_001743465_01230 | Unannotated protein. | Unannotated protein; Belongs to the ALAD family. | 0.999 |
GCA_001743465_03426 | cysG | GCA_001743465_03426 | GCA_001743465_01905 | Unannotated protein. | Unannotated protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.992 |
GCA_001743465_03426 | cysG-2 | GCA_001743465_03426 | GCA_001743465_04422 | Unannotated protein. | Unannotated protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.994 |
GCA_001743465_03426 | hemA | GCA_001743465_03426 | GCA_001743465_00754 | Unannotated protein. | Unannotated protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.991 |
GCA_001743465_03426 | hemE | GCA_001743465_03426 | GCA_001743465_03164 | Unannotated protein. | Unannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.995 |
GCA_001743465_03426 | hemL | GCA_001743465_03426 | GCA_001743465_02163 | Unannotated protein. | Unannotated protein. | 0.957 |
HA41_06880 | HA41_10510 | GCA_001743465_00124 | GCA_001743465_03427 | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.427 |
HA41_06880 | HA41_15145 | GCA_001743465_00124 | GCA_001743465_01230 | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Unannotated protein; Belongs to the ALAD family. | 0.650 |
HA41_06880 | bioF | GCA_001743465_00124 | GCA_001743465_00412 | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Unannotated protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.440 |
HA41_06880 | hemL | GCA_001743465_00124 | GCA_001743465_02163 | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Unannotated protein. | 0.447 |
HA41_07500 | GCA_001743465_03426 | GCA_001743465_00777 | GCA_001743465_03426 | Unannotated protein; Belongs to the precorrin methyltransferase family. | Unannotated protein. | 0.997 |
HA41_07500 | HA41_10510 | GCA_001743465_00777 | GCA_001743465_03427 | Unannotated protein; Belongs to the precorrin methyltransferase family. | Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.975 |
HA41_07500 | HA41_15145 | GCA_001743465_00777 | GCA_001743465_01230 | Unannotated protein; Belongs to the precorrin methyltransferase family. | Unannotated protein; Belongs to the ALAD family. | 0.966 |
HA41_07500 | cysG | GCA_001743465_00777 | GCA_001743465_01905 | Unannotated protein; Belongs to the precorrin methyltransferase family. | Unannotated protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.989 |
HA41_07500 | cysG-2 | GCA_001743465_00777 | GCA_001743465_04422 | Unannotated protein; Belongs to the precorrin methyltransferase family. | Unannotated protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.996 |
HA41_07500 | hemA | GCA_001743465_00777 | GCA_001743465_00754 | Unannotated protein; Belongs to the precorrin methyltransferase family. | Unannotated protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.920 |
HA41_07500 | hemE | GCA_001743465_00777 | GCA_001743465_03164 | Unannotated protein; Belongs to the precorrin methyltransferase family. | Unannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.972 |
HA41_07500 | hemL | GCA_001743465_00777 | GCA_001743465_02163 | Unannotated protein; Belongs to the precorrin methyltransferase family. | Unannotated protein. | 0.924 |