node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCA_001743465_04687 | HA41_03775 | GCA_001743465_04687 | GCA_001743465_00364 | Unannotated protein. | Unannotated protein; Belongs to the citrate synthase family. | 0.959 |
GCA_001743465_04687 | HA41_04125 | GCA_001743465_04687 | GCA_001743465_04674 | Unannotated protein. | Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.963 |
GCA_001743465_04687 | HA41_08200 | GCA_001743465_04687 | GCA_001743465_00711 | Unannotated protein. | Unannotated protein. | 0.993 |
GCA_001743465_04687 | HA41_12600 | GCA_001743465_04687 | GCA_001743465_04751 | Unannotated protein. | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.999 |
GCA_001743465_04687 | HA41_12605 | GCA_001743465_04687 | GCA_001743465_04750 | Unannotated protein. | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.999 |
GCA_001743465_04687 | accA | GCA_001743465_04687 | GCA_001743465_02135 | Unannotated protein. | Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.999 |
GCA_001743465_04687 | acs | GCA_001743465_04687 | GCA_001743465_02005 | Unannotated protein. | Unannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates [...] | 0.963 |
GCA_001743465_04687 | fabH | GCA_001743465_04687 | GCA_001743465_00710 | Unannotated protein. | Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.996 |
GCA_001743465_04687 | sucC | GCA_001743465_04687 | GCA_001743465_00371 | Unannotated protein. | Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.954 |
GCA_001743465_04687 | sucD | GCA_001743465_04687 | GCA_001743465_00372 | Unannotated protein. | Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.953 |
HA41_03775 | GCA_001743465_04687 | GCA_001743465_00364 | GCA_001743465_04687 | Unannotated protein; Belongs to the citrate synthase family. | Unannotated protein. | 0.959 |
HA41_03775 | HA41_04125 | GCA_001743465_00364 | GCA_001743465_04674 | Unannotated protein; Belongs to the citrate synthase family. | Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.929 |
HA41_03775 | HA41_08200 | GCA_001743465_00364 | GCA_001743465_00711 | Unannotated protein; Belongs to the citrate synthase family. | Unannotated protein. | 0.510 |
HA41_03775 | HA41_12600 | GCA_001743465_00364 | GCA_001743465_04751 | Unannotated protein; Belongs to the citrate synthase family. | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.962 |
HA41_03775 | HA41_12605 | GCA_001743465_00364 | GCA_001743465_04750 | Unannotated protein; Belongs to the citrate synthase family. | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.964 |
HA41_03775 | accA | GCA_001743465_00364 | GCA_001743465_02135 | Unannotated protein; Belongs to the citrate synthase family. | Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.956 |
HA41_03775 | acs | GCA_001743465_00364 | GCA_001743465_02005 | Unannotated protein; Belongs to the citrate synthase family. | Unannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates [...] | 0.995 |
HA41_03775 | fabH | GCA_001743465_00364 | GCA_001743465_00710 | Unannotated protein; Belongs to the citrate synthase family. | Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.958 |
HA41_03775 | sucC | GCA_001743465_00364 | GCA_001743465_00371 | Unannotated protein; Belongs to the citrate synthase family. | Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.993 |
HA41_03775 | sucD | GCA_001743465_00364 | GCA_001743465_00372 | Unannotated protein; Belongs to the citrate synthase family. | Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.902 |