Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
sbcDNuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (422 aa)    
Predicted Functional Partners:
Nhal_1979
PFAM: SMC domain protein; KEGG: hch:HCH_00898 ATPase involved in DNA repair.
 
 0.999
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.963
Nhal_0829
PFAM: peptidase C14 caspase catalytic subunit p20; Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; KEGG: hch:HCH_04244 TPR repeat-containing protein.
  
 0.955
Nhal_1022
KEGG: vsp:VS_1367 hypothetical protein.
  
 0.951
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.872
Nhal_1282
KEGG: ypk:y2190 hypothetical protein.
    
  0.810
Nhal_2019
SMART: helicase c2; KEGG: noc:Noc_1364 helicase C2.
   
 0.802
Nhal_3123
PFAM: DNA polymerase III delta subunit; KEGG: noc:Noc_1659 DNA polymerase III subunit delta'.
   
 0.759
Nhal_2023
PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: mxa:MXAN_7274 SNF2/helicase domain-containing protein.
  
 
 0.747
Nhal_3861
Cytochrome b/b6 domain protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
   0.716
Your Current Organism:
Nitrosococcus halophilus
NCBI taxonomy Id: 472759
Other names: N. halophilus Nc 4, Nitrosococcus halophilus Nc 4, Nitrosococcus halophilus str. Nc 4, Nitrosococcus halophilus strain Nc 4
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