STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rneRibonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (785 aa)    
Predicted Functional Partners:
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.827
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
    
 
 0.798
Nhal_0330
Conserved hypothetical protein; Displays ATPase and GTPase activities.
   
 
 0.797
Nhal_0408
PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: AAA ATPase; single-stranded nucleic acid binding R3H domain protein; KEGG: noc:Noc_2975 single-stranded nucleic acid binding R3H.
   
   0.747
Nhal_3500
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: noc:Noc_2611 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family.
    
 
 0.722
rhlB
DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.
    
 
 0.722
Nhal_2637
Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
  
  
 0.518
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
  
 0.492
Nhal_1225
Diguanylate cyclase; KEGG: noc:Noc_1758 PAS sensor diguanylate cyclase/phophodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; response regulator receiver; PAS domain containing protein.
   
 
 0.461
hfq
RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
 
 
 0.444
Your Current Organism:
Nitrosococcus halophilus
NCBI taxonomy Id: 472759
Other names: N. halophilus Nc 4, Nitrosococcus halophilus Nc 4, Nitrosococcus halophilus str. Nc 4, Nitrosococcus halophilus strain Nc 4
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