STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nhal_3537PFAM: FAD dependent oxidoreductase; KEGG: bpy:Bphyt_0284 FAD dependent oxidoreductase. (407 aa)    
Predicted Functional Partners:
Nhal_3489
TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pub:SAR11_1282 sarcosine oxidase alpha chain; Belongs to the GcvT family.
 
 0.994
Nhal_3488
PFAM: Sarcosine oxidase gamma subunit; KEGG: bvi:Bcep1808_7299 sarcosine oxidase, gamma subunit.
 
 0.960
Nhal_2764
PFAM: aminotransferase class V; KEGG: noc:Noc_2128 aminotransferase, class V.
 
 
 0.941
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.917
Nhal_3785
Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: rpe:RPE_1630 aromatic amino acid beta-eliminating lyase/threonine aldolase.
  
  
 0.917
gcvPB
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
   
 
 0.911
gcvPA
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
   
 
 0.904
Nhal_3493
Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: noc:Noc_2606 threonine aldolase.
     
 0.902
Nhal_3490
PFAM: Sarcosine oxidase delta subunit heterotetrameric; KEGG: bxe:Bxe_B1599 SoxD.
 
 
 0.878
Nhal_3525
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
  
 0.837
Your Current Organism:
Nitrosococcus halophilus
NCBI taxonomy Id: 472759
Other names: N. halophilus Nc 4, Nitrosococcus halophilus Nc 4, Nitrosococcus halophilus str. Nc 4, Nitrosococcus halophilus strain Nc 4
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