OIJ21425.1 protein (Anaerobacillus alkalidiazotrophicus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

OIJ21425.1

Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)

Predicted Functional Partners:

OIJ21424.1

0.998

OIJ22448.1

0.998

OIJ21426.1

0.991

OIJ19959.1

0.975

OIJ18480.1

0.975

OIJ22524.1

0.688

OIJ21271.1

0.538

OIJ21278.1

0.538

OIJ21565.1

0.538

OIJ22258.1

0.538

Your Current Organism:

Anaerobacillus alkalidiazotrophicus

NCBI taxonomy Id: 472963
Other names: A. alkalidiazotrophicus, Anaerobacillus alkalidiazotrophicus (Sorokin et al. 2008) Zavarzina et al. 2010, Bacillus alkalidiazotrophicus, Bacillus alkalidiazotrophicus Sorokin et al. 2008, DSM 22531, NCCB 100213, UNIQEM U377, strain MS 6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OIJ18480.1	OIJ21424.1	BKP45_18715	BKP45_01215	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.946
OIJ18480.1	OIJ21425.1	BKP45_18715	BKP45_01225	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.975
OIJ18480.1	OIJ22448.1	BKP45_18715	BKP45_01220	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Branched-chain amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.944
OIJ19959.1	OIJ21424.1	BKP45_13000	BKP45_01215	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.946
OIJ19959.1	OIJ21425.1	BKP45_13000	BKP45_01225	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.975
OIJ19959.1	OIJ22448.1	BKP45_13000	BKP45_01220	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Branched-chain amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.944
OIJ21271.1	OIJ21278.1	BKP45_00355	BKP45_00390	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407
OIJ21271.1	OIJ21425.1	BKP45_00355	BKP45_01225	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.538
OIJ21278.1	OIJ21271.1	BKP45_00390	BKP45_00355	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407
OIJ21278.1	OIJ21425.1	BKP45_00390	BKP45_01225	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.538
OIJ21278.1	OIJ21565.1	BKP45_00390	BKP45_02160	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.647
OIJ21424.1	OIJ18480.1	BKP45_01215	BKP45_18715	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.946
OIJ21424.1	OIJ19959.1	BKP45_01215	BKP45_13000	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.946
OIJ21424.1	OIJ21425.1	BKP45_01215	BKP45_01225	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
OIJ21424.1	OIJ21426.1	BKP45_01215	BKP45_01230	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.982
OIJ21424.1	OIJ22448.1	BKP45_01215	BKP45_01220	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	Branched-chain amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.	0.994
OIJ21425.1	OIJ18480.1	BKP45_01225	BKP45_18715	Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.975
OIJ21425.1	OIJ19959.1	BKP45_01225	BKP45_13000	Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	BMP family ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.975
OIJ21425.1	OIJ21271.1	BKP45_01225	BKP45_00355	Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.538
OIJ21425.1	OIJ21278.1	BKP45_01225	BKP45_00390	Heme ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.538

page 1 of 2

Network Stats

number of nodes:

5

number of edges:

9

average node degree:

3.6

avg. local clustering coefficient:

0.9

expected number of edges:

11

PPI enrichment p-value:

0.465

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:2001295

malonyl-CoA biosynthetic process

2 of 3

2.29

1.15

0.0073

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003700

DNA-binding transcription factor activity

7 of 89

1.36

1.73

3.18e-06

GO:0016743

Carboxyl- or carbamoyltransferase activity

2 of 4

2.17

0.79

0.0348

GO:0003989

acetyl-CoA carboxylase activity

2 of 4

2.17

0.79

0.0348

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009317

acetyl-CoA carboxylase complex

2 of 3

2.29

1.3

0.0038

GO:0005737

Cytoplasm

11 of 1119

0.46

0.38

0.00095

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2244

Mixed, incl. The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PUBMED:12757941. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules., and Peroxiredoxin activity

4 of 6

2.29

2.56

1.08e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01210

2-Oxocarboxylic acid metabolism

4 of 22

1.73

1.76

0.00012

map00300

Lysine biosynthesis

4 of 24

1.69

1.73

0.00012

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009317

acetyl-CoA carboxylase complex

2 of 4

2.17

0.75

0.0419

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0805

Transcription regulation

7 of 113

1.26

1.52

4.72e-06

KW-0238

DNA-binding

7 of 190

1.04

4.98e-05

KW-0275

Fatty acid biosynthesis

2 of 11

1.73

0.71

0.0408

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01039

Carboxyl transferase domain

2 of 2

2.47

0.83

0.0302

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00345

Helix_turn_helix gluconate operon transcriptional repressor

7 of 12

2.23

5.3

2.51e-12

SM00866

The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PUBMED:12757941. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.

4 of 5

2.37

3.23

5.11e-07

SM00895

This entry represents the C-terminal ligand binding domain of many members of the GntR family. This domain probably binds to a range of effector molecules that regulate the transcription of genes through the action of the N-terminal DNA-binding ...

2 of 3

2.29

1.29

0.0040

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