ENSNMLP00000000637 protein (Neogobius melanostomus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

ENSNMLP00000000637

Mitogen-activated protein kinase 10. (216 aa)

Predicted Functional Partners:

ENSNMLP00000016229

0.972

ENSNMLP00000034721

0.963

ENSNMLP00000031292

0.960

ENSNMLP00000021455

0.957

ENSNMLP00000014768

0.952

ENSNMLP00000040198

0.951

ENSNMLP00000001294

0.950

ENSNMLP00000034101

0.950

ENSNMLP00000007364

0.948

ENSNMLP00000018434

0.948

Your Current Organism:

Neogobius melanostomus

NCBI taxonomy Id: 47308
Other names: Apollonia melanostoma, Apollonia melanostomus, Gobius melanostomus, N. melanostomus, round goby

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
ENSNMLP00000000637	ENSNMLP00000001294	Mitogen-activated protein kinase 10.	Mitochondrial ribosomal protein S35.	0.950
ENSNMLP00000000637	ENSNMLP00000007364	Mitogen-activated protein kinase 10.	Mitochondrial ribosomal protein S14.	0.948
ENSNMLP00000000637	ENSNMLP00000014768	Mitogen-activated protein kinase 10.	Mitogen-activated protein kinase kinase 7.	0.952
ENSNMLP00000000637	ENSNMLP00000016229	Mitogen-activated protein kinase 10.	Jun proto-oncogene, AP-1 transcription factor subunit.	0.972
ENSNMLP00000000637	ENSNMLP00000018434	Mitogen-activated protein kinase 10.	3-hydroxyisobutyryl-CoA hydrolase.	0.948
ENSNMLP00000000637	ENSNMLP00000021455	Mitogen-activated protein kinase 10.	Mitochondrial ribosomal protein S11.	0.957
ENSNMLP00000000637	ENSNMLP00000031292	Mitogen-activated protein kinase 10.	Mitochondrial ribosomal protein S12.	0.960
ENSNMLP00000000637	ENSNMLP00000034101	Mitogen-activated protein kinase 10.	Mitochondrial ribosomal protein S16.	0.950
ENSNMLP00000000637	ENSNMLP00000034721	Mitogen-activated protein kinase 10.	Mitochondrial ribosomal protein S5.	0.963
ENSNMLP00000000637	ENSNMLP00000040198	Mitogen-activated protein kinase 10.	Mitochondrial ribosomal protein S15.	0.951
ENSNMLP00000001294	ENSNMLP00000000637	Mitochondrial ribosomal protein S35.	Mitogen-activated protein kinase 10.	0.950
ENSNMLP00000001294	ENSNMLP00000007364	Mitochondrial ribosomal protein S35.	Mitochondrial ribosomal protein S14.	0.999
ENSNMLP00000001294	ENSNMLP00000018434	Mitochondrial ribosomal protein S35.	3-hydroxyisobutyryl-CoA hydrolase.	0.991
ENSNMLP00000001294	ENSNMLP00000021455	Mitochondrial ribosomal protein S35.	Mitochondrial ribosomal protein S11.	0.999
ENSNMLP00000001294	ENSNMLP00000031292	Mitochondrial ribosomal protein S35.	Mitochondrial ribosomal protein S12.	0.998
ENSNMLP00000001294	ENSNMLP00000034101	Mitochondrial ribosomal protein S35.	Mitochondrial ribosomal protein S16.	0.999
ENSNMLP00000001294	ENSNMLP00000034721	Mitochondrial ribosomal protein S35.	Mitochondrial ribosomal protein S5.	0.999
ENSNMLP00000001294	ENSNMLP00000040198	Mitochondrial ribosomal protein S35.	Mitochondrial ribosomal protein S15.	0.999
ENSNMLP00000007364	ENSNMLP00000000637	Mitochondrial ribosomal protein S14.	Mitogen-activated protein kinase 10.	0.948
ENSNMLP00000007364	ENSNMLP00000001294	Mitochondrial ribosomal protein S14.	Mitochondrial ribosomal protein S35.	0.999

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.875

expected number of edges:

11

PPI enrichment p-value:

1.23e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046417

Chorismate metabolic process

7 of 10

2.51

6.15

3.95e-13

GO:0009073

Aromatic amino acid family biosynthetic process

6 of 15

2.27

4.51

3.75e-10

GO:0009423

Chorismate biosynthetic process

5 of 8

2.46

4.25

4.57e-09

GO:0016053

Organic acid biosynthetic process

8 of 158

1.37

2.06

2.70e-08

GO:0008652

Cellular amino acid biosynthetic process

6 of 99

1.45

1.91

2.07e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016838

Carbon-oxygen lyase activity, acting on phosphates

3 of 5

2.45

1.93

0.00025

GO:0003856

3-dehydroquinate synthase activity

2 of 2

2.67

1.16

0.0077

GO:0004106

Chorismate mutase activity

2 of 3

2.49

1.13

0.0085

GO:0003824

Catalytic activity

11 of 2353

0.34

0.26

0.0241

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

9 of 1151

0.56

0.41

0.0065

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:831

Aromatic amino acid family metabolic process, and Anthranilate synthase component I-like

7 of 17

2.28

5.23

6.87e-12

CL:833

Prephenate dehydratase, and Enolpyruvate transferase domain

4 of 5

2.57

3.38

4.03e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00400

Phenylalanine, tyrosine and tryptophan biosynthesis

8 of 25

2.17

5.85

2.40e-14

map01230

Biosynthesis of amino acids

8 of 140

1.42

2.31

3.82e-09

map01110

Biosynthesis of secondary metabolites

8 of 486

0.88

0.85

3.72e-05

map01100

Metabolic pathways

11 of 1481

0.54

0.47

3.85e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005829

Cytosol

6 of 388

0.86

0.59

0.0085

GOCC:0005737

Cytoplasm

9 of 957

0.64

0.49

0.0029

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0057

Aromatic amino acid biosynthesis

4 of 12

2.19

2.69

4.26e-06

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01761

3-dehydroquinate synthase

2 of 2

2.67

0.99

0.0159

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036979

Chorismate mutase domain superfamily

2 of 2

2.67

0.78

0.0384

IPR036263

Chorismate mutase type II superfamily

2 of 2

2.67

0.78

0.0384

IPR030960

3-dehydroquinate synthase domain

2 of 2

2.67

0.78

0.0384

IPR002701

Chorismate mutase II, prokaryotic-type

2 of 2

2.67

0.78

0.0384

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00830

Chorismate mutase type II

2 of 2

2.67

1.37

0.0032

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