ENSNMLP00000002823 protein (Neogobius melanostomus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSNMLP00000002823

annotation not available (152 aa)

Predicted Functional Partners:

ENSNMLP00000044686

0.947

ENSNMLP00000040008

0.939

ENSNMLP00000011891

0.924

ENSNMLP00000012488

0.898

ENSNMLP00000012497

0.898

ENSNMLP00000039860

0.898

ENSNMLP00000025317

0.874

ENSNMLP00000012750

0.867

ENSNMLP00000005314

0.865

ENSNMLP00000026267

0.865

Your Current Organism:

Neogobius melanostomus

NCBI taxonomy Id: 47308
Other names: Apollonia melanostoma, Apollonia melanostomus, Gobius melanostomus, N. melanostomus, round goby

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structured XML interaction data, according to the 'PSI-MI' data standard

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... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
ENSNMLP00000002823	ENSNMLP00000005314	annotation not available	GDP-mannose pyrophosphorylase B.	0.865
ENSNMLP00000002823	ENSNMLP00000011891	annotation not available	annotation not available	0.924
ENSNMLP00000002823	ENSNMLP00000012488	annotation not available	Phosphoglucomutase 3.	0.898
ENSNMLP00000002823	ENSNMLP00000012497	annotation not available	annotation not available	0.898
ENSNMLP00000002823	ENSNMLP00000012750	annotation not available	Endothelial differentiation-related factor 1.	0.867
ENSNMLP00000002823	ENSNMLP00000025317	annotation not available	UDP-galactose-4-epimerase.	0.874
ENSNMLP00000002823	ENSNMLP00000026267	annotation not available	GDP-mannose pyrophosphorylase Aa.	0.865
ENSNMLP00000002823	ENSNMLP00000039860	annotation not available	Phosphoglucomutase 2.	0.898
ENSNMLP00000002823	ENSNMLP00000040008	annotation not available	UDP-glucose 6-dehydrogenase.	0.939
ENSNMLP00000002823	ENSNMLP00000044686	annotation not available	annotation not available	0.947
ENSNMLP00000005314	ENSNMLP00000002823	GDP-mannose pyrophosphorylase B.	annotation not available	0.865
ENSNMLP00000005314	ENSNMLP00000011891	GDP-mannose pyrophosphorylase B.	annotation not available	0.594
ENSNMLP00000005314	ENSNMLP00000012488	GDP-mannose pyrophosphorylase B.	Phosphoglucomutase 3.	0.863
ENSNMLP00000005314	ENSNMLP00000012497	GDP-mannose pyrophosphorylase B.	annotation not available	0.863
ENSNMLP00000005314	ENSNMLP00000025317	GDP-mannose pyrophosphorylase B.	UDP-galactose-4-epimerase.	0.853
ENSNMLP00000005314	ENSNMLP00000026267	GDP-mannose pyrophosphorylase B.	GDP-mannose pyrophosphorylase Aa.	0.995
ENSNMLP00000005314	ENSNMLP00000039860	GDP-mannose pyrophosphorylase B.	Phosphoglucomutase 2.	0.916
ENSNMLP00000005314	ENSNMLP00000040008	GDP-mannose pyrophosphorylase B.	UDP-glucose 6-dehydrogenase.	0.899
ENSNMLP00000005314	ENSNMLP00000044686	GDP-mannose pyrophosphorylase B.	annotation not available	0.961
ENSNMLP00000011891	ENSNMLP00000002823	annotation not available	annotation not available	0.924

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

22

PPI enrichment p-value:

2.95e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 328

1.8

4.86

1.46e-16

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 159

2.07

6.34

2.75e-17

GO:0019843

rRNA binding

3 of 51

2.05

1.36

0.0024

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 184

2.01

5.98

5.37e-17

GO:0044391

Ribosomal subunit

4 of 135

1.75

1.71

0.00019

GO:0015935

Small ribosomal subunit

3 of 46

2.09

1.69

0.00050

GO:0022627

Cytosolic small ribosomal subunit

2 of 18

2.32

1.12

0.0086

GO:1990904

Ribonucleoprotein complex

5 of 555

1.23

1.04

0.0012

(more ...)

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:28942070

(2017) Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A phylogenetic and population-based comparison.

2 of 9

2.62

0.93

0.0209

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15235