ENSNMLP00000024096 protein (Neogobius melanostomus)

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second shell of interactors

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a 3D structure is known or predicted

Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

ENSNMLP00000024096

Transmembrane p24 trafficking protein 1a. (245 aa)

Predicted Functional Partners:

ENSNMLP00000001796

0.789

ENSNMLP00000042451

0.566

ENSNMLP00000024564

0.558

ENSNMLP00000014917

0.556

ENSNMLP00000019458

0.556

ENSNMLP00000040268

0.556

ENSNMLP00000044127

0.556

ENSNMLP00000001111

0.555

ENSNMLP00000018792

0.555

ENSNMLP00000020038

0.555

Your Current Organism:

Neogobius melanostomus

NCBI taxonomy Id: 47308
Other names: Apollonia melanostoma, Apollonia melanostomus, Gobius melanostomus, N. melanostomus, round goby

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
ENSNMLP00000001111	ENSNMLP00000001796	annotation not available	Transmembrane p24 trafficking protein 10.	0.993
ENSNMLP00000001111	ENSNMLP00000024096	annotation not available	Transmembrane p24 trafficking protein 1a.	0.555
ENSNMLP00000001796	ENSNMLP00000001111	Transmembrane p24 trafficking protein 10.	annotation not available	0.993
ENSNMLP00000001796	ENSNMLP00000018792	Transmembrane p24 trafficking protein 10.	Transmembrane p24 trafficking protein 2.	0.993
ENSNMLP00000001796	ENSNMLP00000020038	Transmembrane p24 trafficking protein 10.	annotation not available	0.993
ENSNMLP00000001796	ENSNMLP00000024096	Transmembrane p24 trafficking protein 10.	Transmembrane p24 trafficking protein 1a.	0.789
ENSNMLP00000014917	ENSNMLP00000019458	Wingless-type MMTV integration site family, member 1.	Wingless-type MMTV integration site family, member 4.	0.844
ENSNMLP00000014917	ENSNMLP00000024096	Wingless-type MMTV integration site family, member 1.	Transmembrane p24 trafficking protein 1a.	0.556
ENSNMLP00000014917	ENSNMLP00000024564	Wingless-type MMTV integration site family, member 1.	Wingless-type MMTV integration site family, member 11.	0.676
ENSNMLP00000014917	ENSNMLP00000040268	Wingless-type MMTV integration site family, member 1.	Wingless-type MMTV integration site family, member 8b.	0.668
ENSNMLP00000014917	ENSNMLP00000042451	Wingless-type MMTV integration site family, member 1.	Wingless-type MMTV integration site family, member 6b.	0.675
ENSNMLP00000014917	ENSNMLP00000044127	Wingless-type MMTV integration site family, member 1.	Wingless-type MMTV integration site family, member 16.	0.683
ENSNMLP00000018792	ENSNMLP00000001796	Transmembrane p24 trafficking protein 2.	Transmembrane p24 trafficking protein 10.	0.993
ENSNMLP00000018792	ENSNMLP00000024096	Transmembrane p24 trafficking protein 2.	Transmembrane p24 trafficking protein 1a.	0.555
ENSNMLP00000019458	ENSNMLP00000014917	Wingless-type MMTV integration site family, member 4.	Wingless-type MMTV integration site family, member 1.	0.844
ENSNMLP00000019458	ENSNMLP00000024096	Wingless-type MMTV integration site family, member 4.	Transmembrane p24 trafficking protein 1a.	0.556
ENSNMLP00000019458	ENSNMLP00000024564	Wingless-type MMTV integration site family, member 4.	Wingless-type MMTV integration site family, member 11.	0.642
ENSNMLP00000019458	ENSNMLP00000042451	Wingless-type MMTV integration site family, member 4.	Wingless-type MMTV integration site family, member 6b.	0.645
ENSNMLP00000019458	ENSNMLP00000044127	Wingless-type MMTV integration site family, member 4.	Wingless-type MMTV integration site family, member 16.	0.675
ENSNMLP00000020038	ENSNMLP00000001796	annotation not available	Transmembrane p24 trafficking protein 10.	0.993

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

46

average node degree:

8.36

avg. local clustering coefficient:

0.948

expected number of edges:

47

PPI enrichment p-value:

0.53

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000398

mRNA splicing, via spliceosome

7 of 229

1.81

3.04

2.77e-08

GO:0010467

Gene expression

9 of 1738

1.04

1.14

4.44e-06

GO:0022618

Ribonucleoprotein complex assembly

3 of 155

1.61

0.8

0.0239

GO:0000387

Spliceosomal snRNP assembly

2 of 30

2.15

0.75

0.0415

GO:0034641

Cellular nitrogen compound metabolic process

9 of 3050

0.79

0.67

0.00044

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1990935

Splicing factor binding

2 of 4

3.02

1.34

0.0038

GO:0003723

RNA binding

8 of 1208

1.14

1.24

2.24e-05

GO:0003676

Nucleic acid binding

9 of 3699

0.71

0.53

0.0038

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005686

U2 snRNP

5 of 20

2.72

5.12

1.89e-10

GO:0071011

Precatalytic spliceosome

6 of 53

2.38

4.86

1.24e-10

GO:0005684

U2-type spliceosomal complex

6 of 92

2.14

4.22

5.76e-10

GO:0071005

U2-type precatalytic spliceosome

5 of 48

2.34

4.12

5.07e-09

GO:0005681

Spliceosomal complex

7 of 176

1.92

3.93

1.89e-10

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:18986

U2 snRNP, and Nuclear cap binding complex

6 of 23

2.74

5.91

5.02e-12

CL:18988

U2 snRNP

4 of 12

2.84

4.05

3.05e-08

CL:19002

Splicing factor binding, and PSP, proline-rich

3 of 5

3.1

3.14

1.97e-06

CL:19016

U4 snRNP

2 of 5

2.92

1.53

0.0017

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03040

Spliceosome

7 of 266

1.74

3.21

1.84e-09

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72165

mRNA Splicing - Minor Pathway

6 of 59

2.33

4.64

2.98e-10

MAP-72172

mRNA Splicing

7 of 296

1.7

2.88

1.45e-08

MAP-72203

Processing of Capped Intron-Containing Pre-mRNA

7 of 391

1.57

2.48

5.54e-08

MAP-8953854

Metabolism of RNA

9 of 946

1.3

1.91

1.45e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990904

Ribonucleoprotein complex

9 of 447

1.63

3.22

3.44e-11

GOCC:0097525

Spliceosomal snRNP complex

4 of 40

2.32

2.85

2.87e-06

GOCC:0005681

Spliceosomal complex

4 of 107

1.89

2.04

4.99e-05

GOCC:0005687

U4 snRNP

2 of 6

2.84

1.63

0.0011

GOCC:0005689

U12-type spliceosomal complex

2 of 8

2.72

1.53

0.0016

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0687

Ribonucleoprotein

4 of 93

1.96

2.16

3.14e-05

KW-0694

RNA-binding

4 of 347

1.38

1.06

0.0027

KW-0689

Ribosomal protein

2 of 63

1.82

0.7

0.0469

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