ENSNMLP00000039713 protein (Neogobius melanostomus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSNMLP00000039713

annotation not available (158 aa)

Predicted Functional Partners:

ENSNMLP00000008925

0.474

ENSNMLP00000004042

0.471

ENSNMLP00000008517

0.471

ENSNMLP00000020083

0.471

ENSNMLP00000028606

0.471

ENSNMLP00000043337

0.471

ENSNMLP00000043338

0.471

ENSNMLP00000043339

0.471

ENSNMLP00000043340

0.471

ENSNMLP00000003904

0.449

Your Current Organism:

Neogobius melanostomus

NCBI taxonomy Id: 47308
Other names: Apollonia melanostoma, Apollonia melanostomus, Gobius melanostomus, N. melanostomus, round goby

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structured XML interaction data, according to the 'PSI-MI' data standard

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... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
ENSNMLP00000003904	ENSNMLP00000004042	annotation not available	annotation not available	0.814
ENSNMLP00000003904	ENSNMLP00000008517	annotation not available	Tenascin C.	0.814
ENSNMLP00000003904	ENSNMLP00000008925	annotation not available	Tenascin N.	0.814
ENSNMLP00000003904	ENSNMLP00000020083	annotation not available	Tenascin R (restrictin, janusin).	0.814
ENSNMLP00000003904	ENSNMLP00000028606	annotation not available	annotation not available	0.814
ENSNMLP00000003904	ENSNMLP00000039713	annotation not available	annotation not available	0.449
ENSNMLP00000003904	ENSNMLP00000043337	annotation not available	annotation not available	0.814
ENSNMLP00000003904	ENSNMLP00000043338	annotation not available	annotation not available	0.814
ENSNMLP00000003904	ENSNMLP00000043339	annotation not available	annotation not available	0.814
ENSNMLP00000003904	ENSNMLP00000043340	annotation not available	annotation not available	0.814
ENSNMLP00000004042	ENSNMLP00000003904	annotation not available	annotation not available	0.814
ENSNMLP00000004042	ENSNMLP00000008517	annotation not available	Tenascin C.	0.612
ENSNMLP00000004042	ENSNMLP00000008925	annotation not available	Tenascin N.	0.795
ENSNMLP00000004042	ENSNMLP00000020083	annotation not available	Tenascin R (restrictin, janusin).	0.795
ENSNMLP00000004042	ENSNMLP00000028606	annotation not available	annotation not available	0.959
ENSNMLP00000004042	ENSNMLP00000039713	annotation not available	annotation not available	0.471
ENSNMLP00000004042	ENSNMLP00000043337	annotation not available	annotation not available	0.612
ENSNMLP00000004042	ENSNMLP00000043338	annotation not available	annotation not available	0.855
ENSNMLP00000004042	ENSNMLP00000043339	annotation not available	annotation not available	0.612
ENSNMLP00000004042	ENSNMLP00000043340	annotation not available	annotation not available	0.825

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

49

average node degree:

8.91

avg. local clustering coefficient:

0.915

expected number of edges:

15

PPI enrichment p-value:

2.73e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015344

Siderophore uptake transmembrane transporter activity

4 of 36

1.51

1.08

0.0038

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019867

Outer membrane

4 of 69

1.22

0.81

0.0095

GO:0031975

Envelope

4 of 81

1.15

0.77

0.0095

GO:0030312

External encapsulating structure

4 of 89

1.11

0.75

0.0095

GO:0009279

Cell outer membrane

3 of 55

1.2

0.66

0.0274

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2807

Mixed, incl. CarboxypepD_reg-like domain, and TonB, C-terminal

8 of 11

2.32

6.51

5.58e-15

CL:2805

Mixed, incl. CarboxypepD_reg-like domain, and TonB, C-terminal

9 of 20

2.11

5.89

4.17e-15

CL:2792

Mixed, incl. TonB-dependent receptor-like, beta-barrel domain superfamily, and Magnesium chelatase activity

10 of 54

1.73

4.25

5.63e-15

CL:2790

Mixed, incl. TonB-dependent receptor-like, beta-barrel domain superfamily, and Magnesium chelatase activity

11 of 84

1.58

3.57

4.17e-15

CL:2809

Mixed, incl. Methyltransferase, class D, and Tricarboxylic acid metabolic process

4 of 5

2.36

3.31

3.42e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009279

Cell outer membrane

4 of 72

1.21

0.7

0.0209

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0675

Receptor

4 of 42

1.44

1.11

0.0025

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR008969

Carboxypeptidase-like, regulatory domain superfamily

4 of 33

1.54

1.01

0.0065

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