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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
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cbiDcobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (370 aa)    
Predicted Functional Partners:
KZX14619.1
Cobalamin biosynthesis protein CbiG.
 
 
 0.999
cobK
precorrin-6A reductase.
 
 
 0.996
cbiH_1
cobalt-precorrin-3B C(17)-methyltransferase.
 
 
 0.984
cbiT
Putative cobalt-precorrin-6Y C(15)-methyltransferase; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
 
 0.982
cbiH_2
cobalt-precorrin-3B C(17)-methyltransferase.
 
 
 0.977
cobH
precorrin-8X methylmutase.
 
  
 0.976
cbiF
Cobalt-precorrin-4 C(11)-methyltransferase.
 
 
 0.974
cbiL
Cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.957
cobB_2
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
  
 0.865
KZX17381.1
Glutaredoxin.
     
 0.815
Your Current Organism:
Methanobrevibacter cuticularis
NCBI taxonomy Id: 47311
Other names: DSM 11139, M. cuticularis, strain RFM-1
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