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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfo_1Endonuclease 4. (261 aa)    
Predicted Functional Partners:
iolX
Scyllo-inositol 2-dehydrogenase.
  
 
 0.930
tarI
Putative ribitol-5-phosphate cytidylyltransferase.
  
  
 0.737
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.694
lgrB
Linear gramicidin synthase subunit B.
  
 
 0.686
iolC
5-dehydro-2-deoxygluconokinase; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.665
adoK
Adenosine kinase.
  
 
 0.665
fucA
L-fuculose phosphate aldolase.
  
 
 0.560
exoA_1
Exodeoxyribonuclease.
     
 0.529
exoA_2
Exodeoxyribonuclease.
     
 0.529
fae
5,6,7,8-tetrahydromethanopterin hydro-lyase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family.
  
 
  0.528
Your Current Organism:
Methanobrevibacter cuticularis
NCBI taxonomy Id: 47311
Other names: DSM 11139, M. cuticularis, strain RFM-1
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