Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
albA-2DNA/RNA-binding protein albA; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (92 aa)    
Predicted Functional Partners:
KZX14618.1
Hypothetical protein; Belongs to the UPF0147 family.
  
     0.669
cmk_2
Cytidylate kinase; Belongs to the archaeal adenylate kinase family.
  
     0.642
KZX15439.1
PAC2 family protein.
  
    0.633
KZX15925.1
Hypothetical protein.
  
     0.617
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
       0.610
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
       0.586
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
   
 0.545
KZX14881.1
Hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
      
 0.526
leuA_1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
       0.507
KZX17147.1
Histone-like transcription factor (CBF/NF-Y) and archaeal histone.
  
   
 0.501
Your Current Organism:
Methanobrevibacter cuticularis
NCBI taxonomy Id: 47311
Other names: DSM 11139, M. cuticularis, strain RFM-1
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