STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
KZX15102.1Putative oxidoreductasec; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. (403 aa)    
Predicted Functional Partners:
cyoE
Protoheme IX farnesyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
 
 
 0.993
carS
Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
     
 0.979
kmo
Kynurenine 3-monooxygenase.
  
  
 
0.889
KZX15103.1
Ferredoxin-1.
  
  
 0.805
bchI_2
Magnesium-chelatase 38 kDa subunit.
 
  
 0.770
ispB
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.647
tarI
Putative ribitol-5-phosphate cytidylyltransferase.
  
 
 0.642
KZX16312.1
2-oxoglutarate-acceptor oxidoreductase subunit OorD.
 
   
 0.615
cobN
Aerobic cobaltochelatase subunit CobN.
 
  
 0.576
lgrB
Linear gramicidin synthase subunit B.
  
  
 0.574
Your Current Organism:
Methanobrevibacter cuticularis
NCBI taxonomy Id: 47311
Other names: DSM 11139, M. cuticularis, strain RFM-1
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