STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDQ64901.1DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (297 aa)    
Predicted Functional Partners:
SDR27517.1
Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain.
   
    0.793
SDQ64927.1
Arsenate reductase; Belongs to the ArsC family.
       0.773
SDR19859.1
Two-component system, OmpR family, KDP operon response regulator KdpE.
  
    0.773
SDQ64947.1
Protein of unknown function.
       0.767
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
       0.767
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
     
 0.767
SDQ72205.1
DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
   
 0.743
SDQ68710.1
DNA-binding transcriptional regulator, MarR family.
   
    0.741
SDQ64878.1
Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
 
     0.734
SDQ46446.1
DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
   
 0.733
Your Current Organism:
Tsukamurella pulmonis
NCBI taxonomy Id: 47312
Other names: ATCC 700081, CCUG 35732, CIP 104791, DSM 44142, DSM 44990 [[Tsukamurella spongiae]], JCM 10111, JCM 14882 [[Tsukamurella spongiae]], NCTC 13230, NRRL B-24467 [[Tsukamurella spongiae]], T. pulmonis, Tsukamurella sp. K362, Tsukamurella spongiae, Tsukamurella spongiae Olson et al. 2007, strain K362 [[Tsukamurella spongiae]]
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.