STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDR28894.1DNA-binding transcriptional regulator, MerR family. (240 aa)    
Predicted Functional Partners:
SDQ75258.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.758
SDQ92812.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.758
SDQ42118.1
DNA-binding transcriptional regulator, MerR family.
  
     0.741
SDR22265.1
acetyl-CoA carboxylase carboxyl transferase subunit beta.
   
  0.715
SDQ79727.1
DNA-binding transcriptional regulator, MerR family.
  
     0.684
SDR01839.1
DNA-binding transcriptional regulator, MerR family.
  
     0.631
SDR24651.1
DNA-binding transcriptional regulator, MerR family.
  
     0.622
SDQ59058.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.584
SDR28882.1
Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
       0.584
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
   0.583
Your Current Organism:
Tsukamurella pulmonis
NCBI taxonomy Id: 47312
Other names: ATCC 700081, CCUG 35732, CIP 104791, DSM 44142, DSM 44990 [[Tsukamurella spongiae]], JCM 10111, JCM 14882 [[Tsukamurella spongiae]], NCTC 13230, NRRL B-24467 [[Tsukamurella spongiae]], T. pulmonis, Tsukamurella sp. K362, Tsukamurella spongiae, Tsukamurella spongiae Olson et al. 2007, strain K362 [[Tsukamurella spongiae]]
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